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Figure 5 | Clinical Epigenetics

Figure 5

From: Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients

Figure 5

Association between expression of ABCA1 and survival in ovarian cancer patients. Expression of ABCA1 in 55 ovarian cancer patient samples was determined by IHC in tissue microarray. (A) Representative image of ovarian cancer showing high (left panel) and low (right panel) ABCA1 expression on the cell membrane or cytoplasm (×400). (B) Kaplan-Meier analysis found that patients with low ABCA1 expression have shorter progression-free survival than patients with high ABCA1 expression (P = 0.038). (C) Similar results can be observed in TCGA ovarian cancer RNA-Seq dataset that patients with low expression of ABCA1 are associated with shorter overall survival (P = 0.0008). Log-rank P values are shown.

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Clinical Epigenetics

ISSN: 1868-7083

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