Table 8 The effects of changes in DNA methylation on asthma transition between ages 10 and 18
Gene | CpG sites | Effects on transition; Log-OR (P value) | |
|---|---|---|---|
(−,+)# | (+,–)$ | ||
Dynamic methylation | |||
GATA3 | cg13543854 | 1.69 (0.22) | −0.58 (0.78) |
IL4R | cg26937798 | −3.11 (0.069) | 3.97 (0.074) |
IL4 | cg23943829 | 3.56 (0.11) | −0.99 (0.73) |
Stable methylation | |||
GATA3 | cg12405139 | −1.60 (0.64) | 1.06 (0.71) |
IL4R | cg09791102 | −21.18 (1.00) | −0.67 (0.47) |