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Table 5 The effects of SNP, DNA methylation, and their interactions in selected models ( GATA3 )

From: The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition

     Effects at age 10 (n = 34) Effects at age 18 (n = 233)
Model Model frequency# Parameter   Estimate (log OR) P value$ Estimate (log OR) P value$
1 5 cg13543854   −20.27 0.19 3.21 0.066
rs568727 AA NA NA 27.47 0.37
CC 123.62 0.04 −11.50 0.20
AC Ref.   Ref. Ref.
cg13543854* rs568727 AA NA NA 9.42 0.36
CC 40.76 0.04 −3.52 0.21
AC Ref.   Ref.  
2 27 cg12405139   −12.15 0.049 −0.02 0.99
rs2229359 AG −47.21 1.00 −13.86 1.00
AA NA NA −22.39 0.36
GG Ref.   Ref. Ref.
cg12405139* rs2229359 AG 12.15 1.00 0.02 1.00
AA NA NA 8.58 0.37
GG Ref.   Ref. Ref.
  1. #The frequency is based on 1,000 bootstrap samples.
  2. $P values significant at the 0.01 level at age 18 are in bold font.