Skip to main content
Figure 1 | Clinical Epigenetics

Figure 1

From: Allelic variation in the canine Cox-2 promoter causes hypermethylation of the canine Cox-2 promoter in clinical cases of renal dysplasia

Figure 1

Allelic variants in the cyclooxygenase-2 (Cox- 2) promoter, just upstream of the ATG translation start site. Allelic variant 1 has DNA sequences that are deleted; these sequences are boxed with the number 1 below the box. Allelic variants 2 and 3 contain insertions. Allele 2 is underlined and not shaded. Allele 3 contains a further insertion of sequences at nucleotide -78 relative to the ATG start, and is a duplication of the inserted sequences in allele 2. Allelic variant 4 contains a deletion of 6 nucleotides (CCGCCG) and is boxed and marked with the number 4 below the box. The sequences of the complete promoter region and 5′ untranslated region are deposited in GenBank under accession number AY927786.1.

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us