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Figure 2 | Clinical Epigenetics

Figure 2

From: 11p15 DNA-methylation analysis in monozygotic twins with discordant intrauterine development due to severe twin-to-twin transfusion syndrome

Figure 2

Intra-individual correlation of single CpG methylation levels within and between regions. Spearman’s correlation coefficients are indicated graphically. Correlation coefficients within regions were: saliva - KCNQ1OT1, R = 0.814, P < 0.01; H19, R = 0.527, P < 0.01; blood - IGF2 dmr0, R = 0.559, P < 0.01; KCNQ1OT1, R = 0.748, P < 0.01; LINE-1, R = 0.539, P < 0.01). Significant correlations or trends (P < 0.1) for relations within one sample but between regions were: saliva - IGF2 dmr0 SN1 × H19prom SN12, R = 0.335, P = 0.075; KCNQ1OT1 - SN16 × LINE-1 SN1, R = 0.410, P = 0.016; H19prom SN5 × LINE-1 SN13, R = 0.400, P = 0.031; H19prom SN12 × LINE-1 SN13, R = 0.469, P = 0.010; blood - IGF2 dmr0 SN1 × H19prom SN12, R = -0.329, P = 0.038).

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Clinical Epigenetics

ISSN: 1868-7083

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