Table 2 Summary and test statistics for the 12 sentinel CpG sites comparing never with current smokers
From: Differences in smoking associated DNA methylation patterns in South Asians and Europeans
Target ID | Chr | Location (bp)a | Gene ID or region | Relation to CpG island | Median β-values (IQR) all samples | Effect size (%)b | F-statisticc | P-valuec | Rank | |
|---|---|---|---|---|---|---|---|---|---|---|
Never smokers | Current smokers | |||||||||
cg09069072 | 1 | 15482753 | TMEM51 | South Shore | 0.85 (0.82, 0.87) | 0.79 (0.75, 0.83) | -0.06 | 31.49 | 8.5 × 10-8 | 11 |
cg25189904 | 1 | 68299493 | GNG12 | South Shore | 0.25 (0.20, 0.32) | 0.18 (0.16, 0.22) | -0.07 | 35.05 | 1.9 × 10-8 | 7 |
cg09935388 | 1 | 92947588 | GFI1 | CpG Island | 0.57 (0.42, 0.75) | 0.27 (0.21, 0.38) | -0.30 | 47.85 | 1.0 × 10-10 | 6 |
cg21566642 | 2 | 233284661 | 2q37.1 | CpG Island | 0.49 (0.43, 0.52) | 0.32 (0.28, 0.37) | -0.16 | 172.13 | 3.0 × 10-27 | 2 |
cg03274391 | 3 | 22413232 | 3p24.3 | North Shore | 0.31 (0.21, 0.44) | 0.56 (0.34, 0.75) | +0.25 | 34.56 | 2.3 × 10-8 | 8 |
cg05575921 | 5 | 373378 | AHRR | North Shore | 0.77 (0.74, 0.79) | 0.55 (0.52, 0.58) | -0.22 | 658.31 | 6.1 × 10-59 | 1 |
cg13039251 | 5 | 32018601 | PDZD2 |  | 0.71 (0.65, 0.79) | 0.83 (0.76, 0.89) | +0.11 | 33.46 | 3.7 × 10-8 | 9 |
cg06126421 | 6 | 30720080 | 6p21.33 |  | 0.75 (0.64, 0.82) | 0.52 (0.41, 0.66) | -0.23 | 63.64 | 2.6 × 10-13 | 5 |
cg17619755 | 6 | 31760629 | VARS | North Shelf | 0.61 (0.57, 0.65) | 0.67 (0.63, 0.72) | +0.05 | 31.89 | 7.2 × 10-8 | 10 |
cg22132788 | 7 | 45002486 | MYO1G | CpG Island | 0.83 (0.76, 0.89) | 0.95 (0.90, 0.97) | +0.12 | 89.85 | 3.1 × 10-17 | 4 |
cg01731783 | 14 | 74211788 | C14orf43 |  | 0.40 (0.35, 0.43) | 0.33 (0.31, 0.37) | -0.07 | 31.46 | 8.6 × 10-8 | 12 |
cg03636183 | 19 | 17000585 | F2RL3 | North Shore | 0.36 (0.31, 0.40) | 0.23 (0.20, 0.28) | -0.12 | 93.30 | 1.0 × 10-17 | 3 |