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Figure 2 | Clinical Epigenetics

Figure 2

From: Hypomethylation and overexpression of ITGAL (CD11a) in CD4+ T cells in systemic sclerosis

Figure 2

Schematic representation of the CD11a gene promoter locus. The 23 potentially methylated CpG pairs in the CD11a promoter sequences are identified by the lollipop-shaped figures. The region including Alu elements is denoted by the horizontal line. The transcriptionally relevant PU1, C/EBP, Sp1 transcription factor, ets-related factor, PEBP2/CBF/AML family of transcription factor, RUNX3, and RUNX1/AML-1 transcription factor binding sites and the transcription start site are also shown.

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