Figure 1From: LINE-1 hypomethylation is neither present in rectal aberrant crypt foci nor associated with field defect in sporadic colorectal neoplasiaStudy design. Flow chart summarizing the study design. Long interspersed element-1 (LINE-1) methylation analysis was performed in DNA extracted from aberrant crypt foci (ACF) and normal colorectal mucosa samples from three colon cancer risk groups (individuals with a normal colonoscopy, patients with adenomas, and patients with colon cancer).Back to article page