Gene | % Methylation (n) | Publication | Methodologyb | Correlation with outcomec |
---|---|---|---|---|
ABO | 33 (30) | [28] | MSP, MCA | - |
APC | 9-71% | Â | Â | Â |
13 (47) | [29] | MSP | - | |
17 (79) | [30] | MS-MLPA | N | |
71 (84)d | [31] | MSP | - | |
15 (34) | [22] | MSP, MCA | - | |
18 (77) | [27] | Nested MSP | N | |
9 (126)e | [32] | MS-MLPA | - | |
ATM | 0-88% | Â | Â | Â |
42 (24)f | [33] | MSP | - | |
88 (84)d | [31] | MSP | - | |
0 (37) | [34] | Pyrosequencing | - | |
25 (100) | [18] | MSP | W | |
1 (126 )e | [32] | MS-MLPA | - | |
BRCA1 | 0-95% | Â | Â | Â |
95 (58)d | [20] | Pyrosequencing | - | |
0 (89) | [35] | MSP | - | |
0 (126)e | [32] | MS-MLPA | - | |
CDH1 | 0-88% | Â | Â | Â |
0 (32) | [36] | MSP | - | |
18 (48) | [37] | qMSP | N | |
88 (43) | [38] | MSP | - | |
33 (340)f | [39] | MSP | I | |
13 (38) | [40] | MSP | I | |
43 (54) | [41] | MSP | - | |
62 (76) | [42] | MSP | - | |
64 (86) | [25] | RE-MSP | Wg | |
78 (23) | [43] | MSP | - | |
43 (190) | [9] | MSP | N | |
42 (47) | [29] | MSP | - | |
43 (77) | [27] | Nested MSP | W | |
38 (37) | [34] | Pyrosequencing | - | |
42 (79) | [44] | Pyrosequencing | - | |
36 (80) | [45] | MSP | - | |
66 (33)h | [46] | qMSP | N | |
35 (99) | [47] | RE-MSP | - | |
35 (55)f | [48] | MSP | - | |
CDH13 | 10-34% | Â | Â | Â |
34 (79) | [30] | MS-MLPA | N | |
10 (126)e | [32] | MS-MLPA | - | |
CDKN2A (P16) | 0-95% | Â | Â | Â |
38 (56) | [49] | MSP | - | |
49 (73) | [50] | MSP | N | |
36 (47) | [51] | MSP | N | |
49 (51) | [52] | MSP | - | |
12 (61) | [53] | MSP | N | |
48 (92) | [54] | qMSP | - | |
22 (48) | [37] | qMSP | N | |
78 (40)h | [55] | MSP | N | |
13 (79) | [30] | MS-MLPA | N | |
63 (43) | [38] | MSP | - | |
5 (42) | [40] | MSP | N | |
60 (54) | [41] | MSP | - | |
87 (38) | [7] | MSP | - | |
17 (24)f | [56] | MSP | - | |
27 (56 )h | [57] | RE-MSP | - | |
79 (75) | [58] | MSP | I | |
20 (20) | [59] | MSP | - | |
44 (126) | [9] | MSP | N | |
59 (47) | [29] | MSP | - | |
58 (77) | [27] | Nested MSP | N | |
95 (41) | [60] | MSP | - | |
26 (37) | [34] | Pyrosequencing | - | |
28 (79) | [44] | Pyrosequencing | - | |
24 (45)f | [61] | MSP | - | |
20 (20) | [62] | RE-MSP | - | |
33 (80) | [45] | MSP | - | |
29 (96) | [63] | MSPi | N | |
47 (30) | [10] | MSP | - | |
29 (116) | [64] | MSP | W | |
27 (95) | [65] | MSP | - | |
20 (121) | [66] | MSP | - | |
29 (52)h | [46] | qMSP | W | |
23 (99) | [47] | RE-MSP | N | |
8 (51)f | [48] | MSP | - | |
23 (30) | [67] | RE-MSP | - | |
0 (126)e | [32] | MS-MLPA | - | |
DAPK1 | 7-81% | Â | Â | Â |
14 (79) | [30] | MS-MLPA | N | |
81 (43) | [38] | MSP | - | |
11 (44) | [40] | MSP | N | |
60 (54) | [41] | MSP | - | |
76 (41) | [68] | MSP | - | |
42 (290) | [9] | MSP | N | |
37 (77) | [27] | Nested MSP | N | |
30 (47) | [29] | MSP | - | |
19 (32) | [36] | MSP | - | |
45 (20) | [59] | MSP | - | |
39 (18) | [60] | MSP | - | |
24 (80) | [45] | MSP | - | |
7 (96) | [63] | MSPi | N | |
33 (30) | [10] | MSP | - | |
18 (95) | [65] | MSP | - | |
42 (33)h | [46] | qMSP | N | |
20 (49)f | [48] | MSP | - | |
12 (126)e | [32] | MS-MLPA | - | |
ERCC1 | 51 (84) | [19] | MSP | N |
MGMT | 18-74% | Â | Â | Â |
30 (47) | [51] | MSP | N | |
53 (51) | [52] | MSP | - | |
10 (20) | [53] | Pyrosequencing | Wj | |
30 (88) | [53] | MSP | Wj | |
36 (44)h | [69] | MSP | - | |
31 (32) | [36] | MSP | - | |
43 (40) | [40] | MSP | N | |
53 (54) | [41] | MSP | - | |
74 (76) | [42] | MSP | - | |
50 (20) | [59] | MSP | - | |
27 (212) | [9] | MSP | N | |
54 (41) | [68] | MSP | - | |
31 (37) | [34] | Pyrosequencing | - | |
28 (21) | [70] | MSP | - | |
23 (30) | [10] | MSP | - | |
33 (95) | [65] | MSP | - | |
21 (33)h | [46] | qMSP | N | |
38 (47) | [29] | MSP | - | |
34 (77) | [27] | Nested MSP | N | |
41 (99) | [47] | RE-MSP | - | |
25 (52)f | [48] | MSP | - | |
18 (94) | [71] | MSP | W | |
MLH1 | 0-88% | Â | Â | Â |
26 (47) | [29] | MSP | - | |
18 (28) | [72] | MSP | - | |
0 (20) | [73] | RE-MSP | - | |
23 (62) | [49] | MSP | - | |
23 (47) | [51] | MSP | N | |
47 (116)e | [74] | RE-MSP | - | |
37 (123) | [75] | RE-MSP | - | |
88 (8) | [76] | MSP | - | |
69 (54) | [41] | MSP | - | |
0 (37) | [34] | Pyrosequencing | - | |
29 (49) | [17] | MSP | - | |
76 (50) | [77] | MSP | - | |
0 (96) | [63] | MSPi | N | |
8 (99) | [47] | RE-MSP | - | |
14 (43)f | [48] | MSP | - | |
0 (126)e | [32] | MS-MLPA | - | |
RASSF1A | 0-44% | Â | Â | Â |
17 (24) | [78] | RE-MSP | - | |
12 (66) | [53] | MSP | N | |
2 (41) | [40] | MSP | N | |
18 (54) | [41] | MSP | - | |
0 (32) | [36] | MSP | - | |
32 (41) | [68] | MSP | - | |
38 (47) | [27] | MSP | - | |
44 (18) | [60] | MSP | - | |
22 (482)h | [8] | dHPLC | N | |
8 (80) | [45] | MSP | - | |
33 (33)h | [46] | qMSP | N | |
6 (50)f | [48] | MSP | - | |
11 (126)e | [32] | MS-MLPA | - | |
RUNX3 | 18-70% | Â | Â | Â |
70 (30) | [79] | MSP | - | |
26 (47) | [29] | MSP | - | |
25 (76) | [21] | MSP | N | |
18 (45)f | [61] | MSP | - |