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Figure 2 | Clinical Epigenetics

Figure 2

From: Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome

Figure 2

Pyrosequencing results for all samples demonstrating heterogeneous methylation of RUNX3 when assessed by methylation sensitive high resolution melting (MS-HRM). Each analyzed sample is annotated for the quantity of methylation detected at each CpG site interrogated, and the mean methylation value for all CpG sites analyzed is also provided. This figure demonstrates that the vast majority of samples with heterogeneous methylation for this locus assessed by MS-HRM, had low levels of methylation when quantified by pyrosequencing.

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Clinical Epigenetics

ISSN: 1868-7083

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