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Figure 9 | Clinical Epigenetics

Figure 9

From: Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection

Figure 9

S. aureus induces selective enrichment of H3K14 acetylation at specific gene promoters. Acetylated H3K14 are selectively enriched at the promoters of the immune genes upon SA1 infection in the mice mammary tissue. ChIP assays were done with acetylated H3K9, H3K14, and H4K8 antibodies along with IgG controls in the tissue sections of S. aureus infected mice mammary tissue. The fold difference in expression of the genes in infected tissue over the PBS control tissue was calculated and plotted as the average of three biological replicates for SA1 and two biological replicates for SA2.

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