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Table 1 A summary of the IGFBP1 DNA methylation and IGFBP-1 serum levels in Swedish men with normal glucose tolerance, type 1 and type 2 diabetes

From: Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathy

Group

Number

IGFBP1 DNA methylation levels (%)

P value

IGFBP-1 serum levels (μg/L)

P value

Reference

T2D

164

20.0 (19.5-20.5)

P < 0.001

18 (16-20)

0.014

Gu T et al. 2013 [19]

NGT

242

16.9 (16.4-17.1)

-

24 (21–26)

-

 

T1D

304

15.6 (15.1-16.1)

P < 0.001

31 (28–35)

0.007

Present study

  1. Data are presented as means (95% CI). NGT, normal glucose tolerance; T1D, type 1 diabetes; T2D, type 2 diabetes; P values were from comparison tests of NGT versus T1D or T2D and adjusted for age.
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Clinical Epigenetics

ISSN: 1868-7083

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