Figure 3From: Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathyIGFBP1 DNA methylation changes and serum protein variation in Swedish type 1 diabetes patients with and without diabetic nephropathy. A and B demonstrated the similar IGFBP1 DNA methylation levels between T1D with and without DN in either male (16.4% versus 15.4%; P = 0.186 adjusted for age) or female patients (15.9% versus 15.6%, P = 0.604, adjusted for age). C and D indicate that the IGFBP-1 serum levels in T1D patients with DN were significantly increased in both male (52 μg/L versus 28 μg/L; P = 0.021) and female patients (71 μg/L versus 33 μg/L; P = 0.003), in comparison with T1D patients without DN.Back to article page