Figure 1From: Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathyIGFBP1 DNA methylation changes and serum protein variation in Swedish men with normal glucose tolerance and type 1 diabetes. (A) The mean levels of IGFBP1 DNA methylation in T1D patients were significantly lower than those in NGT subjects (15.6% versus 16.9%; P < 0.001, adjusted for age). (B) IGFBP-1 serum levels in T1D patients were increased compared with subjects with NGT (31 μg/L versus 24 μg/L; P = 0.005).Back to article page