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Table 2 The 30 most significantly associated probes in DNA from men

From: Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking

Probe ID Gene Placement Island status Average beta values t test Corrected P value
     Smoker Nonsmoker   
cg05575921 AHRR Body N shore 0.74 0.85 4.92 × 10−9 0.002
cg21161138 AHRR Body   0.69 0.73 1.18 × 10−7 0.029
cg26703534 AHRR Body S shelf 0.64 0.69 4.72 × 10−7 0.076
cg22132788 MYO1G Body Island 0.94 0.88 1.19 × 10−6 0.144
cg17072268 PLD3 TSS1500 N shore 0.82 0.84 1.11 × 10−5 0.999
cg12108912 TMEM177 TSS1500 N shore 0.79 0.80 1.33 × 10−5 0.999
cg12803068 MYO1G Body S shore 0.83 0.76 1.61 × 10−5 0.999
cg22904815    N shore 0.44 0.48 1.65 × 10−5 0.999
cg25628057 ATAD3B Body S shore 0.87 0.88 3.04 × 10−5 0.999
cg04521543 TMEM18 3'UTR   0.83 0.82 3.29 × 10−5 0.999
cg11270237    N shore 0.34 0.36 3.61 × 10−5 0.999
cg00498653    Island 0.15 0.17 3.80 × 10−5 0.999
cg22537081 TBRG4 TSS200 Island 0.03 0.03 3.94 × 10−5 0.999
cg23311108     0.33 0.36 5.29 × 10−5 0.999
cg27312872 C1orf212 Body N shelf 0.83 0.84 5.50 × 10−5 0.999
cg13960339 ZIM2 TSS200 Island 0.51 0.53 6.27 × 10−5 0.999
cg07918390 GPSM3 TSS1500 Island 0.04   6.60 × 10−5 0.999
cg16148833     0.72 0.74 6.85 × 10−5 0.999
cg27072683 NDUFB8 TSS1500 S shore 0.25 0.27 7.28 × 10−5 0.999
cg16579844 RNASE4 1stExon S shore 0.04 0.04 7.54 × 10−5 0.999
cg08939942     0.91 0.92 7.59 × 10−5 0.999
cg25202390 MRPL30 1stExon Island 0.18 0.16 9.23 × 10−5 0.999
cg04097463    S shelf 0.84 0.86 9.76 × 10−5 0.999
cg19192585    Island 0.03 0.03 9.78 × 10−5 0.999
cg18075691    N shelf 0.41 0.36 9.87 × 10−5 0.999
cg20215007 ZNF467 5'UTR N shore 0.19 0.21 0.0002 0.999
cg11467141    Island 0.95 0.92 0.0002 0.999
cg00534919 C1orf26 Body   0.10 0.10 0.000113816 0.999
cg08771171 CTNNA1 Body   0.80 0.82 0.0001182 0.999
cg21029030 MIF4GD TSS1500 Island 0.02 0.02 0.000118582 0.999
  1. All average methylation values are non-log transformed beta values. Island status refers to the position of the probe relative to the island. Classes include: 1) Island, 2) N (north) shore, 3) S (south) shore, 4) N (north shelf), 5) S (south) shelf and 6) blank, denoting that the probe does not map to an island.
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