Table 2 Subject characteristics with available methylation data compared to the female participants of the total cohort
Total female participants n (%) | Female with DNA methylation data, n (%) | P value | |
|---|---|---|---|
Factors | n = 750 | n = 245 | |
Maternal history of asthma | |||
Yes | 80 (10.8) | 30 (12.3) | 0.50 |
No | 662 (89.2) | 213 (87.7) | |
Missing | 8 | 2 | |
Maternal smoking during pregnancy | |||
Yes | 188 (25.3) | 47 (19.3) | 0.05 |
No | 555 (74.7) | 197 (80.7) | |
Missing | 7 | 1 | |
Maternal body mass index (kg/m2) | |||
Underweight (<18.5) | 10 (1.7) | 4 (2.2) | 0.82 |
Normal (18.5- <25) | 355 (61.5) | 109 (59.2) | |
Overweight (≥25.00) | 212 (36.7) | 71 (38.6) | |
Missing | 173 | 61 | |
Low birth weight | |||
Yes | 35 (4.8) | 9 (3.8) | 0.53 |
No | 699 (95.2) | 228 (96.2) | |
Missing | 16 | 8 | |
Asthma at age 18 years | |||
Yes | 128 (19.4) | 35 (14.3) | 0.07 |
No | 531 (80.6) | 210 (85.7) | |
Missing | 91 | 0 | |
Median (5%, 95% value); n | |||
Breastfeeding duration (weeks) | 8.0 (0, 40); 664 | 10.5 (0, 40); 222 | 0.16 |
Missing | 86 | 20 | |
Body mass index at age 18 (kg/m2) | 22.2 (18, 32); 499 | 22.9 (19.05, 32.93); 240 | 0.56 |
Missing | 251 | 5 | |