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Table 2 Subject characteristics with available methylation data compared to the female participants of the total cohort

From: The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

  Total female participants n (%) Female with DNA methylation data, n (%) P value
Factors n = 750 n = 245  
Maternal history of asthma
Yes 80 (10.8) 30 (12.3) 0.50
No 662 (89.2) 213 (87.7)  
Missing 8 2  
Maternal smoking during pregnancy
Yes 188 (25.3) 47 (19.3) 0.05
No 555 (74.7) 197 (80.7)  
Missing 7 1  
Maternal body mass index (kg/m2)
Underweight (<18.5) 10 (1.7) 4 (2.2) 0.82
Normal (18.5- <25) 355 (61.5) 109 (59.2)  
Overweight (≥25.00) 212 (36.7) 71 (38.6)  
Missing 173 61  
Low birth weight
Yes 35 (4.8) 9 (3.8) 0.53
No 699 (95.2) 228 (96.2)  
Missing 16 8  
Asthma at age 18 years
Yes 128 (19.4) 35 (14.3) 0.07
No 531 (80.6) 210 (85.7)  
Missing 91 0  
Median (5%, 95% value); n
Breastfeeding duration (weeks) 8.0 (0, 40); 664 10.5 (0, 40); 222 0.16
Missing 86 20  
Body mass index at age 18 (kg/m2) 22.2 (18, 32); 499 22.9 (19.05, 32.93); 240 0.56
Missing 251 5