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Table 1 Location, position, and distance between the SNPs and the CpG sites in the IL4R gene

From: The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

   CpG sites
   08932316 05729093 03980304 00090800 06641959 01706029 26937798 16649560 08317580 09791102 01165142 05903710
   TSS1500/ N_Shore TSS1500/ Island TSS1500/ Island TSS200/ Island 5UTR/ Island 5UTR/ Island 5UTR/ S_Shore 5UTR 5UTR Body Body 3UTR
   Median, IQR (5%, 95%)
   0.89, 0.02 (0.86, 0.92) 0.06, 0.01 (0.04, 0.08) 0.07, 0.02 (0.04, 0.10) 0.03, 0.01 (0.01, 0.05) 0.08, 0.02 (0.05, 0.11) 0.07, 0.01 (0.05, 0.09) 0.09, 0.02 (0.06, 0.12) 0.21, 0.05 (0.15, 0.29) 0.90, 0.02 (0.87, 0.93) 0.88, 0.02 (0.85, 0.91) 0.58, 0.05 (0.51, 0.65) 0.87, 0.02 (0.84, 0.90)
SNPs Location # 27324341 27324953 27325000 27325237 27325254 27325672 27326054 27338391 27345891 27353414 27367172 27375732
rs2057768
5UTR 27322095 −2246 −2858 −2905 −3142 −3159 −3577 −3959 −16296 −23796 −31319 −45077 −53637
rs6498012
Intron 27331974 7633 7021 6974 6737 6720 6302 5920 −6417 −13917 −21440 −35198 −43758
rs3024622
Intron 27365453 41112 40500 40453 40216 40199 39781 39399 27062 19562 12039 −1719 −10279
rs4787423
Intron 27367334 42993 42381 42334 42097 42080 41662 41280 28943 21443 13920 162 −8398
rs3024676
Coding 27373558 49217 48605 48558 48321 48304 47886 47504 35167 27667 20144 6386 −2174
rs3024685
3UTR 27376910 52569 51957 51910 51673 51656 51238 50856 38519 31019 23496 9738 1178
rs12102586
3UTR 27378053 53712 53100 53053 52816 52799 52381 51999 39662 32162 24639 10881 2321
rs16976728
3UTR 27381712 57371 56759 56712 56475 56458 56040 55658 43321 35821 28298 14540 5980
  1. #The location is based on Build 37, also known as GRCh37. The distance was calculated by subtracting the location of the SNP to the CpG site in the IL4R gene. For instance, the distance between the SNP rs6498012 and the CpG site cg08932316 is 7633 (27331974–27324341).