Figure 3From: Secondhand smoke in combination with ambient air pollution exposure is associated with increasedx CpG methylation and decreased expression of IFN-γ in T effector cells and Foxp3 in T regulatory cells in childrenDiagrammatic representation of Foxp3 promoter and intronic regions [NM_014009: NCBI]. Vertical arrows indicate cytosine neighboring guanine (CpG) dinucleotide sequences that can be potentially methylated. The position of each CpG dinucleotide site is illustrated in relation to the transcription start, which is indicated as +1 bp (base pair).Back to article page