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Table 4 IGF-II concentrations in supernatant from cultured skin fibroblasts

From: IGF2/H19 hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome

 

IGF-II (ng/ml)

SRS patients

Short side a

Long side

S1

5.6b ± 0.4

4.7 ± 0.2

S2

8.2 ± 1.1

6.4 ± 0.1

S3

3.4 ± 0.3

8.8 ± 0.9

S5

2.6 ± 0.1

3.4 ± 0.3

Mean S1 to S5

4.9c ± 2.5

5.8 ± 2.3

5.4 ±2.3

Controls

L

R

K1

6.4 ± 0.2

ndd

K2

5.1 ± 1.8

3.9 ± 0.6

K3

5.4 ± 0.8

4.1 ± 0.4

Mean K1 to K3

5.0 ±1.0

  1. aFor location of short body side see Table 1; bmean of two experiments; cP-value > 0.6 for comparison between short side and long side, as well as for comparison between SRS and control groups; dnd = not done. SRS, Silver-Russell syndrome; L, left; R, right.