Figure 1From: Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutationMSP analysis of the four SFRP genes in MPN-derived cell lines and normal peripheral blood (PB). In vitro methylated DNA (IVD) and water served as controls. Lane U, amplified product with primers recognizing unmethylated SFRP-1, -2, -4, and -5 sequences. Lane M, amplified product with primers recognizing methylated SFRP-1, -2, -4, and -5 sequences.Back to article page