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Table 2 Relationship between ATM promptor methylation and clinicopathology parameters in healthy controls and cases.

From: Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma

Characteristics

Controls

N = 57

ATM methylation status

P value

Cases

N = 84

ATM methylation status

*P

value

  

Present

N (%)

Absent

N (%)

  

Present

N (%)

Absent

N (%)

 

Mean age

39.07 ± 14

   

54.14 ± 18

   

< 50

46

36(78.26)

10(21.74)

0.3

26

23(88.46)

3(11.54)

0.103

> 50

11

8(72.72)

3(27.28)

 

58

51(87.93)

7(12.07)

 

Sex

        

Male

21

17(80.95)

4(19.05)

0.6

40

34(85)

6(15)

0.404

Female

36

27(75)

9(25)

 

44

40(90.90)

4(9.1)

 

Stage

        

I

    

18

16(88.88)

2(11.12)

0.465

II

-

-

-

-

18

15(83.32)

3(16.68)

 

III

    

43

38(83.36)

5(11.64)

 

IV

    

5

5(100)

0

 
  1. *Chi-square test