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Table 2 Relationship between ATM promptor methylation and clinicopathology parameters in healthy controls and cases.

From: Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma

Characteristics Controls
N = 57
ATM methylation status P value Cases
N = 84
ATM methylation status *P
value
   Present
N (%)
Absent
N (%)
   Present
N (%)
Absent
N (%)
 
Mean age 39.07 ± 14     54.14 ± 18    
< 50 46 36(78.26) 10(21.74) 0.3 26 23(88.46) 3(11.54) 0.103
> 50 11 8(72.72) 3(27.28)   58 51(87.93) 7(12.07)  
Sex         
Male 21 17(80.95) 4(19.05) 0.6 40 34(85) 6(15) 0.404
Female 36 27(75) 9(25)   44 40(90.90) 4(9.1)  
Stage         
I      18 16(88.88) 2(11.12) 0.465
II - - - - 18 15(83.32) 3(16.68)  
III      43 38(83.36) 5(11.64)  
IV      5 5(100) 0  
  1. *Chi-square test