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Table 1 Relationship between APC promptor methylation and clinicopathology parameters in healthy controls and cases.

From: Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma

Characteristics Controls * APC Methylation status P value Cases APC methylation status **P
value
  N = 57   N=84      
   Present
N (%)
Absent
N (%)
   Present
N (%)
Absent
N (%)
 
Mean age 39.07 ± 14     54.14 ± 18    
< 50 46 39 (84.8) 7 (15.2)   26 20(76.93) 6 (23.07)  
     0.9     0.2
> 50 11 10(90.90) 1 (9.1)   58 39(67.24) 19(32.76)  
Sex         
Male 21 18 (85.7) 3 (14.3)   39 32(82.05) 7 (17.95)  
     0.06     0.72
Female 36 32(88.88) 4 (11.12)   45 28(62.22) 17(37.78)  
Stage         0.05
I - - - - 18 11(61.11) 7(38.89)  
II      18 15(83.33) 3(16.64)  
III      43 31(72.08) 12(27.92)  
IV      5 2(40) 3(60)  
  1. * Methylation present: means that PCR product is produced only with methylated primers.
  2. Methylation absent: means that PCR product is produced only with unmethylated primers.
  3. **Chi-square test