TY - JOUR AU - Heinen, C. D. AU - Schmutte, C. AU - Fishel, R. PY - 2002 DA - 2002// TI - DNA repair and tumorigenesis: lessons from hereditary cancer syndromes JO - Cancer Biol Ther VL - 1 ID - Heinen2002 ER - TY - JOUR AU - Cazaux, C. PY - 2010 DA - 2010// TI - Genetic instability as a driver for oncogenesis JO - Bull Cancer VL - 97 ID - Cazaux2010 ER - TY - CHAP AU - Barbie, D. A. AU - Hahn, W. C. AU - Pellman, D. S. ED - DeVita, V. T. ED - Lawrence, T. S. ED - Rosenberg, S. A. PY - 2008 DA - 2008// TI - Destabilization of the cancer genome BT - Cancer: Principles & Practice of Oncology PB - Wilkins CY - Philadelphia ID - Barbie2008 ER - TY - JOUR AU - Mangerich, A. AU - Bürkle, A. PY - 2011 DA - 2011// TI - How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation JO - Int J Cancer VL - 128 ID - Mangerich2011 ER - TY - JOUR AU - Rassool, F. V. AU - Tomkinson, A. E. PY - 2010 DA - 2010// TI - Targeting abnormal DNA double strand break repair in cancer JO - Cell Mol Life Sci VL - 67 ID - Rassool2010 ER - TY - JOUR AU - Lord, C. J. AU - Ashworth, A. PY - 2008 DA - 2008// TI - Targeted therapy for cancer using PARP inhibitors JO - Curr Opin Pharmacol VL - 8 ID - Lord2008 ER - TY - JOUR AU - Plummer, R. PY - 2010 DA - 2010// TI - Perspective on the pipeline of drugs being developed with modulation of DNA damage as a target JO - Clin Cancer Res VL - 16 ID - Plummer2010 ER - TY - JOUR AU - Putiri, E. L. AU - Robertson, K. D. PY - 2010 DA - 2010// TI - Epigenetic mechanisms and genome stability JO - Clin Epigenet VL - 2 ID - Putiri2010 ER - TY - JOUR AU - Purrucker, J. C. AU - Mahlknecht, U. PY - 2010 DA - 2010// TI - Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells JO - Clin Epigenet VL - 1 ID - Purrucker2010 ER - TY - JOUR AU - Lichtenstein, A. V. PY - 2010 DA - 2010// TI - Cancer: evolutionary, genetic and epigenetic aspects JO - Clin Epigenet VL - 1 ID - Lichtenstein2010 ER - TY - JOUR AU - Chi, P. AU - Allis, C. D. AU - Wang, G. G. PY - 2010 DA - 2010// TI - Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers JO - Nat Rev Cancer VL - 10 ID - Chi2010 ER - TY - JOUR AU - Zhu, Q. AU - Wani, A. A. PY - 2010 DA - 2010// TI - Histone modifications: crucial elements for damage response and chromatin restoration JO - J Cell Physiol VL - 223 ID - Zhu2010 ER - TY - JOUR AU - Vaissière, T. AU - Herceg, Z. PY - 2010 DA - 2010// TI - Histone code in the cross-talk during DNA damage signaling JO - Cell Res VL - 20 ID - Vaissière2010 ER - TY - JOUR AU - Eot-Houllier, G. AU - Fulcrand, G. AU - Magnaghi-Jaulin, L. AU - Jaulin, C. PY - 2009 DA - 2009// TI - Histone deacetylase inhibitors and genomic instability JO - Cancer Lett VL - 274 ID - Eot-Houllier2009 ER - TY - JOUR AU - Kothapalli, N. AU - Sarath, G. AU - Zempleni, J. PY - 2005 DA - 2005// TI - Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells JO - J Nutr VL - 135 ID - Kothapalli2005 ER - TY - JOUR AU - Kachhap, S. K. AU - Rosmus, N. AU - Collis, S. J. AU - Kortenhorst, M. S. AU - Wissing, M. D. AU - Hedayati, M. PY - 2010 DA - 2010// TI - Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor JO - PLoS One VL - 5 ID - Kachhap2010 ER - TY - JOUR AU - Jang, E. R. AU - Choi, J. D. AU - Park, M. A. AU - Jeong, G. AU - Cho, H. AU - Lee, J. S. PY - 2010 DA - 2010// TI - ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response JO - Exp Mol Med VL - 42 ID - Jang2010 ER - TY - JOUR AU - Ogiwara, H. AU - Ui, A. AU - Otsuka, A. AU - Satoh, H. AU - Yokomi, I. AU - Nakajima, S. AU - Yasui, A. AU - Yokota, J. AU - Kohno, T. PY - 2011 DA - 2011// TI - Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors JO - Oncogene VL - 30 ID - Ogiwara2011 ER - TY - JOUR AU - Rossetto, D. AU - Truman, A. W. AU - Kron, S. J. AU - Côté, J. PY - 2010 DA - 2010// TI - Epigenetic modifications in double-strand break DNA damage signaling and repair JO - Clin Cancer Res VL - 16 ID - Rossetto2010 ER - TY - JOUR AU - Robert, T. AU - Vanoli, F. AU - Chiolo, I. AU - Shubassi, G. AU - Bernstein, K. A. AU - Rothstein, R. AU - Botrugno, O. A. PY - 2011 DA - 2011// TI - HDACs link the DNA damage response, processing of double-strand breaks and autophagy JO - Nature VL - 471 ID - Robert2011 ER - TY - JOUR AU - Kaidi, A. AU - Weinert, B. T. AU - Choudhary, C. AU - Jackson, S. P. PY - 2010 DA - 2010// TI - Human SIRT6 promotes DNA end resection through CtIP deacetylation JO - Science VL - 329 ID - Kaidi2010 ER - TY - JOUR AU - Soerjomataram, I. AU - Oomen, D. AU - Lemmens, V. AU - Oenema, A. AU - Benetou, V. AU - Trichopoulou, A. AU - Coebergh, J. W. AU - Barendregt, J. AU - de Vries, E. PY - 2010 DA - 2010// TI - Increased consumption of fruit and vegetables and future cancer incidence in selected European countries JO - Eur J Cancer VL - 46 ID - Soerjomataram2010 ER - TY - JOUR AU - Miller, P. E. AU - Lesko, S. M. AU - Muscat, J. E. AU - Lazarus, P. AU - Hartman, T. J. PY - 2010 DA - 2010// TI - Dietary patterns and colorectal adenoma and cancer risk: a review of the epidemiological evidence JO - Nutr Cancer VL - 62 ID - Miller2010 ER - TY - CHAP AU - Steevens, J. AU - Schouten, L. J. AU - Goldbohm, R. A. AU - van den Brandt, P. A. PY - 2011 DA - 2011// TI - Vegetables and fruits consumption and risk of esophageal and gastric cancer subtypes in the Netherlands cohort study BT - Int J Cancer ID - Steevens2011 ER - TY - JOUR AU - Büchner, F. L. AU - Bueno-de-Mesquita, H. B. AU - Linseisen, J. AU - Boshuizen, H. C. PY - 2010 DA - 2010// TI - Fruits and vegetables consumption and the risk of histological subtypes of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) JO - Cancer Causes Control VL - 21 ID - Büchner2010 ER - TY - JOUR AU - Rajendran, P. AU - Williams, D. E. AU - Ho, E. AU - Dashwood, R. H. PY - 2011 DA - 2011// TI - Metabolism as a key to histone deacetylase inhibition JO - Crit Rev Biochem Mol Biol VL - 46 ID - Rajendran2011 ER - TY - JOUR AU - Meeran, S. M. AU - Ahmed, A. AU - Tollefsbol, T. O. PY - 2010 DA - 2010// TI - Epigenetic targets of bioactive dietary components for cancer prevention and therapy JO - Clin Epigenetics VL - 1 ID - Meeran2010 ER - TY - CHAP AU - Huang, J. AU - Plass, C. AU - Gerhäuser, C. PY - 2010 DA - 2010// TI - Cancer chemoprevention by targeting the epigenome BT - Curr Drug Targets ID - Huang2010 ER - TY - JOUR AU - Link, A. AU - Balaguer, F. AU - Goel, A. PY - 2010 DA - 2010// TI - Cancer chemoprevention by dietary polyphenols: promising role for epigenetics JO - Biochem Pharmacol VL - 80 ID - Link2010 ER - TY - JOUR AU - Pogribny, I. P. AU - Basnakian, A. G. AU - Miller, B. J. AU - Lopatina, N. G. AU - Poirier, L. A. AU - James, S. J. PY - 1995 DA - 1995// TI - Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats JO - Cancer Res VL - 55 ID - Pogribny1995 ER - TY - JOUR AU - Bonnesen, C. AU - Eggleston, I. M. AU - Hayes, J. D. PY - 2001 DA - 2001// TI - Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines JO - Cancer Res VL - 61 ID - Bonnesen2001 ER - TY - JOUR AU - Antosiewicz, J. AU - Ziolkowski, W. AU - Kar, S. AU - Powolny, A. A. AU - Singh, S. V. PY - 2008 DA - 2008// TI - Role of reactive oxygen intermediates in cellular responses to dietary cancer chemopreventive agents JO - Planta Med VL - 74 ID - Antosiewicz2008 ER - TY - JOUR AU - Jeggo, P. A. PY - 1998 DA - 1998// TI - DNA breakage and repair JO - Adv Genet VL - 38 ID - Jeggo1998 ER - TY - JOUR AU - Rogakou, E. P. AU - Pilch, D. R. AU - Orr, A. H. AU - Ivanova, V. S. AU - Bonner, W. M. PY - 1998 DA - 1998// TI - DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 JO - J Biol Chem VL - 273 ID - Rogakou1998 ER - TY - JOUR AU - Rogakou, E. P. AU - Boon, C. AU - Redon, C. AU - Bonner, W. M. PY - 1999 DA - 1999// TI - Megabase chromatin domains involved in DNA double-strand breaks in vivo JO - J Cell Biol VL - 146 ID - Rogakou1999 ER - TY - JOUR AU - Burma, S. AU - Chen, B. P. AU - Murphy, M. AU - Kurimasa, A. AU - Chen, D. J. PY - 2001 DA - 2001// TI - ATM phosphorylates histone H2AX in response to DNA doublestrand breaks JO - J Biol Chem VL - 276 ID - Burma2001 ER - TY - JOUR AU - Ward, I. M. AU - Chen, J. PY - 2001 DA - 2001// TI - Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress JO - J Biol Chem VL - 276 ID - Ward2001 ER - TY - JOUR AU - Tamburini, B. A. AU - Tyler, J. K. PY - 2005 DA - 2005// TI - Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair JO - Mol Cell Biol VL - 25 ID - Tamburini2005 ER - TY - JOUR AU - Yamamoto, T. AU - Horikoshi, M. PY - 1997 DA - 1997// TI - Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60 JO - J Biol Chem VL - 272 ID - Yamamoto1997 ER - TY - JOUR AU - Kimura, A. AU - Horikoshi, M. PY - 1998 DA - 1998// TI - Tip60 acetylates six lysines of a specific class in core histones in vitro JO - Genes Cells VL - 3 ID - Kimura1998 ER - TY - JOUR AU - Miller, K. M. AU - Tjeertes, J. V. AU - Coates, J. AU - Legube, G. AU - Polo, S. E. AU - Britton, S. AU - Jackson, S. P. PY - 2010 DA - 2010// TI - Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining JO - Nat Struct Mol Biol VL - 17 ID - Miller2010 ER - TY - JOUR AU - Bhaskara, S. AU - Knutson, S. K. AU - Jiang, G. AU - Chandrasekharan, M. B. AU - Wilson, A. J. AU - Zheng, S. PY - 2010 DA - 2010// TI - HDAC3 is essential for the maintenance of chromatin structure and genome stability JO - Cancer Cell VL - 18 ID - Bhaskara2010 ER - TY - JOUR AU - Kotian, S. AU - Liyanarachchi, S. AU - Zelent, A. AU - Parvin, J. D. PY - 2011 DA - 2011// TI - Histone deacetylases 9 and 10 are required for homologous recombination JO - J Biol Chem VL - 286 ID - Kotian2011 ER - TY - JOUR AU - Shen, X. AU - Mizuguchi, G. AU - Hamiche, A. AU - Wu, C. PY - 2000 DA - 2000// TI - A chromatin remodelling complex involved in transcription and DNA processing JO - Nature VL - 406 ID - Shen2000 ER - TY - JOUR AU - Krogan, N. J. AU - Keogh, M. C. AU - Datta, N. AU - Sawa, C. AU - Ryan, O. W. AU - Ding, H. PY - 2003 DA - 2003// TI - A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1 JO - Mol Cell VL - 12 ID - Krogan2003 ER - TY - JOUR AU - Krogan, N. J. AU - Baetz, K. AU - Keogh, M. C. AU - Datta, N. AU - Sawa, C. PY - 2004 DA - 2004// TI - Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 JO - Proc Natl Acad Sci USA VL - 101 ID - Krogan2004 ER - TY - JOUR AU - Paul, T. T. AU - Rogakou, E. P. AU - Yamazaki, V. AU - Kirchgessner, C. U. AU - Gellert, M. AU - Bonner, W. M. PY - 2000 DA - 2000// TI - A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage JO - Curr Biol VL - 10 ID - Paul2000 ER - TY - JOUR AU - Petrini, J. H. PY - 2007 DA - 2007// TI - Cell signaling JO - A touching response to damage. Science VL - 316 ID - Petrini2007 ER - TY - JOUR AU - Essers, J. AU - Houtsmuller, A. B. AU - van Veelen, L. AU - Paulusma, C. AU - Nigg, A. L. AU - Pastink, A. AU - Vermeulen, W. AU - H, H. o. e. i. j. m. a. k. e. r. s. J. AU - Kanaar, R. PY - 2002 DA - 2002// TI - Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage JO - Embo J VL - 21 ID - Essers2002 ER - TY - JOUR AU - Yu, D. S. AU - Sonoda, E. AU - Takeda, S. AU - Huang, C. L. AU - Pellegrini, L. AU - Blundell, T. L. AU - Venkitaraman, A. R. PY - 2003 DA - 2003// TI - Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2 JO - Mol Cell VL - 12 ID - Yu2003 ER - TY - JOUR AU - Lee, J. H. AU - Paull, T. T. PY - 2005 DA - 2005// TI - ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex JO - Science VL - 308 ID - Lee2005 ER - TY - JOUR AU - Sobhian, B. AU - Shao, G. AU - Lilli, D. R. AU - Culhane, A. C. AU - Moreau, L. A. AU - Xia, B. AU - Livingston, D. M. AU - Greenberg, R. A. PY - 2007 DA - 2007// TI - RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites JO - Science VL - 316 ID - Sobhian2007 ER - TY - JOUR AU - Wang, B. AU - Matsuoka, S. AU - Ballif, B. A. AU - Zhang, D. AU - Smogorzewska, A. AU - Gygi, S. P. AU - Elledge, S. J. PY - 2007 DA - 2007// TI - Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response JO - Science VL - 316 ID - Wang2007 ER - TY - JOUR AU - Ayoub, N. AU - Jeyasekharan, A. D. AU - Bernal, J. A. AU - Venkitaraman, A. R. PY - 2008 DA - 2008// TI - HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response JO - Nature VL - 453 ID - Ayoub2008 ER - TY - JOUR AU - Sun, Y. AU - Jiang, X. AU - Xu, Y. AU - Ayrapetov, M. K. AU - Moreau, L. A. AU - Whetstine, J. R. AU - Price, B. D. PY - 2009 DA - 2009// TI - Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60 JO - Nat Cell Biol VL - 11 ID - Sun2009 ER - TY - JOUR AU - Ziv, Y. AU - Bielopolski, D. AU - Galanty, Y. AU - Lukas, C. AU - Taya, Y. AU - Schultz, D. C. AU - Lukas, J. AU - Bekker-Jensen, S. AU - Bartek, J. AU - Shiloh, Y. PY - 2006 DA - 2006// TI - Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway JO - Nat Cell Biol VL - 8 ID - Ziv2006 ER - TY - JOUR AU - Chen, C. C. AU - Carson, J. J. AU - Feser, J. AU - Tamburini, B. AU - Zabaronick, S. AU - Linger, J. AU - Tyler, J. K. PY - 2008 DA - 2008// TI - Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair JO - Cell VL - 134 ID - Chen2008 ER - TY - JOUR AU - Utley, R. T. AU - Lacoste, N. AU - Jobin-Robitaille, O. AU - Allard, S. AU - Côté, J. PY - 2005 DA - 2005// TI - Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4 JO - Mol Cell Biol VL - 25 ID - Utley2005 ER - TY - JOUR AU - Ayoub, N. AU - Rajendra, E. AU - Su, X. AU - Jeyasekharan, A. D. AU - Mahen, R. AU - Venkitaraman, A. R. PY - 2009 DA - 2009// TI - The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry JO - Curr Biol VL - 19 ID - Ayoub2009 ER - TY - JOUR AU - Shi, W. AU - Ma, Z. AU - Willers, H. AU - Akhtar, K. AU - Scott, S. P. AU - Zhang, J. AU - Powell, S. PY - 2008 DA - 2008// TI - Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation JO - J Biol Chem VL - 283 ID - Shi2008 ER - TY - JOUR AU - Gallinari, P. AU - Di Marco, S. AU - Jones, P. AU - Pallaoro, M. AU - Steinkuhler, C. PY - 2007 DA - 2007// TI - HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics JO - Cell Res VL - 17 ID - Gallinari2007 ER - TY - JOUR AU - Goodarzi, A. A. AU - Noon, A. T. AU - Jeggo, P. A. PY - 2009 DA - 2009// TI - The impact of heterochromatin on DSB repair JO - Biochem Soc Trans VL - 37 ID - Goodarzi2009 ER - TY - JOUR AU - Marks, P. A. AU - Xu, W. S. PY - 2009 DA - 2009// TI - Histone deacetylase inhibitors: Potential in cancer therapy JO - J Cell Biochem VL - 107 ID - Marks2009 ER - TY - JOUR AU - Ito, A. AU - Kawaguchi, Y. AU - Lai, C. H. AU - Kovacs, J. J. AU - Higashimoto, Y. AU - Appella, E. AU - Yao, T. P. PY - 2002 DA - 2002// TI - MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation JO - EMBO J VL - 21 ID - Ito2002 ER - TY - JOUR AU - Milutinovic, S. AU - Zhuang, Q. AU - Szyf, M. PY - 2002 DA - 2002// TI - Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification JO - J Biol Chem VL - 277 ID - Milutinovic2002 ER - TY - JOUR AU - Yarden, R. I. AU - Brody, L. C. PY - 1999 DA - 1999// TI - BRCA1 interacts with components of the histone deacetylase complex JO - Proc Natl Acad Sci USA VL - 96 ID - Yarden1999 ER - TY - JOUR AU - Kim, G. D. AU - Choi, Y. H. AU - Dimtchev, A. AU - Jeong, S. J. AU - Dritschilo, A. AU - Jung, M. PY - 1999 DA - 1999// TI - Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase JO - J Biol Chem VL - 274 ID - Kim1999 ER - TY - JOUR AU - Schmidt, D. R. AU - Schreiber, S. L. PY - 1999 DA - 1999// TI - Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4 JO - Biochemistry VL - 38 ID - Schmidt1999 ER - TY - JOUR AU - Vieyra, D. AU - Loewith, R. AU - Scott, M. AU - Bonnefin, P. AU - Boisvert, F. M. AU - Cheema, P. AU - Pastyryeva, S. PY - 2002 DA - 2002// TI - Human ING1 proteins differentially regulate histone acetylation JO - J Biol Chem VL - 277 ID - Vieyra2002 ER - TY - JOUR AU - Anderson, L. A. AU - Perkins, N. D. PY - 2002 DA - 2002// TI - The large subunit of replication factor C interacts with the histone deacetylase, HDAC1 JO - J Biol Chem VL - 277 ID - Anderson2002 ER - TY - JOUR AU - Bhakat, K. K. AU - Mantha, A. K. AU - Mitra, S. PY - 2009 DA - 2009// TI - Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein JO - Antioxid Redox Signal VL - 11 ID - Bhakat2009 ER - TY - JOUR AU - Bhaskara, S. AU - Chyla, B. J. AU - Amann, J. M. AU - Knutson, S. K. AU - Cortez, D. AU - Sun, Z. W. AU - Hiebert, S. W. PY - 2008 DA - 2008// TI - Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control JO - Mol Cell VL - 30 ID - Bhaskara2008 ER - TY - JOUR AU - Codina, A. AU - Love, J. D. AU - Li, Y. AU - Lazar, M. A. AU - Neuhaus, D. AU - Schwabe, J. W. PY - 2005 DA - 2005// TI - Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors JO - Proc Natl Acad Sci USA VL - 102 ID - Codina2005 ER - TY - JOUR AU - Jones, P. L. AU - Shi, Y. B. PY - 2003 DA - 2003// TI - N-CoR-HDAC corepressor complexes: roles in transcriptional regulation by nuclear hormone receptors JO - Curr Top Microbiol Immunol VL - 274 ID - Jones2003 ER - TY - JOUR AU - Ishii, S. AU - Kurasawa, Y. AU - Wong, J. AU - Yu-Lee, L. Y. PY - 2008 DA - 2008// TI - Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment JO - Proc Natl Acad Sci USA VL - 105 ID - Ishii2008 ER - TY - JOUR AU - Eot-Houllier, G. AU - Fulcrand, G. AU - Watanabe, Y. AU - Magnaghi-Jaulin, L. AU - Jaulin, C. PY - 2008 DA - 2008// TI - Histone deacetylase 3 is required for centromeric H3K4 deacetylation and sister chromatid cohesion JO - Genes Dev VL - 22 ID - Eot-Houllier2008 ER - TY - JOUR AU - Conti, C. AU - Leo, E. AU - Eichler, G. S. AU - Sordet, O. AU - Martin, M. M. AU - Fan, A. AU - Aladjem, M. I. AU - Pommier, Y. PY - 2010 DA - 2010// TI - Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage JO - Cancer Res VL - 70 ID - Conti2010 ER - TY - JOUR AU - Kao, G. D. AU - McKenna, W. G. AU - Guenther, M. G. AU - Muschel, R. J. AU - Lazar, M. A. AU - Yen, T. J. PY - 2003 DA - 2003// TI - Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response JO - J Cell Biol VL - 160 ID - Kao2003 ER - TY - JOUR AU - Basile, V. AU - Mantovani, R. AU - Imbriano, C. PY - 2006 DA - 2006// TI - DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines JO - J Biol Chem VL - 281 ID - Basile2006 ER - TY - JOUR AU - Namdar, M. AU - Perez, G. AU - Ngo, L. AU - Marks, P. A. PY - 2010 DA - 2010// TI - Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents JO - Proc Natl Acad Sci USA VL - 107 ID - Namdar2010 ER - TY - JOUR AU - Palacios, J. A. AU - Herranz, D. AU - De Bonis, M. L. AU - Velasco, S. AU - Serrano, M. AU - Blasco, M. A. PY - 2010 DA - 2010// TI - SIRT1 contributes to telomere maintenance and augments global homologous recombination JO - J Cell Biol VL - 191 ID - Palacios2010 ER - TY - JOUR AU - Uhl, M. AU - Csernok, A. AU - Aydin, S. AU - Kreienberg, R. AU - Wiesmüller, L. AU - Gatz, S. A. PY - 2010 DA - 2010// TI - Role of SIRT1 in homologous recombination JO - DNA repair VL - 9 ID - Uhl2010 ER - TY - JOUR AU - Yamamori, T. AU - DeRicco, J. AU - Naqvi, A. AU - Hoffman, T. A. AU - Mattagajasingh, I. AU - Kasuno, K. AU - Jung, S. B. AU - Kim, C. S. AU - Irani, K. PY - 2010 DA - 2010// TI - SIRT1 deacetylates APE1 and regulates cellular base excision repair JO - Nucleic Acids Res VL - 38 ID - Yamamori2010 ER - TY - JOUR AU - Tennen, R. I. AU - Chua, K. F. PY - 2011 DA - 2011// TI - Chromatin regulation and genome maintenance by mammalian SIRT6 JO - Trends Biochem Sci VL - 36 ID - Tennen2011 ER - TY - JOUR AU - Ford, J. AU - Jiang, M. AU - Milner, J. PY - 2005 DA - 2005// TI - Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival JO - Cancer Res VL - 65 ID - Ford2005 ER - TY - JOUR AU - Luo, J. AU - Nikolaev, A. Y. AU - Imai, S. AU - Chen, D. AU - Su, F. AU - Shiloh, A. AU - Guarente, L. AU - Gu, W. PY - 2001 DA - 2001// TI - Negative control of p53 by Sir2alpha promotes cell survival under stress JO - Cell VL - 107 ID - Luo2001 ER - TY - JOUR AU - Vaziri, H. AU - Dessain, S. K. AU - Ng Eaton, E. AU - Imai, S. I. AU - Frye, R. A. AU - Pandita, T. K. AU - Guarente, L. AU - Weinberg, R. A. PY - 2001 DA - 2001// TI - hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase JO - Cell VL - 107 ID - Vaziri2001 ER - TY - JOUR AU - Brunet, A. AU - Sweeney, L. B. AU - Sturgill, J. F. AU - Chua, K. F. AU - Greer, P. L. AU - Lin, Y. AU - Tran, H. PY - 2004 DA - 2004// TI - Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase JO - Science VL - 303 ID - Brunet2004 ER - TY - JOUR AU - Motta, M. C. AU - Divecha, N. AU - Lemieux, M. AU - Kamel, C. AU - Chen, D. AU - Gu, W. AU - Bultsma, Y. AU - McBurney, M. AU - Guarente, L. PY - 2004 DA - 2004// TI - Mammalian SIRT1 represses forkhead transcription factors JO - Cell VL - 116 ID - Motta2004 ER - TY - JOUR AU - Jeong, J. AU - Juhn, K. AU - Lee, H. AU - Kim, S. H. AU - Min, B. H. AU - Lee, K. M. AU - Cho, M. H. AU - Park, G. H. AU - Lee, K. H. PY - 2007 DA - 2007// TI - SIRT1 promotes DNA repair activity and deacetylation of Ku70 JO - Exp Mol Med VL - 39 ID - Jeong2007 ER - TY - JOUR AU - Wang, J. AU - Chen, J. PY - 2010 DA - 2010// TI - SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60 JO - J Biol Chem VL - 285 ID - Wang2010 ER - TY - JOUR AU - Yuan, J. AU - Pu, M. AU - Zhang, Z. AU - Lou, Z. PY - 2009 DA - 2009// TI - Histone H3-K56 acetylation is important for genomic stability in mammals JO - Cell Cycle VL - 8 ID - Yuan2009 ER - TY - JOUR AU - Yuan, Z. AU - Zhang, X. AU - Sengupta, N. AU - Lane, W. S. AU - Seto, E. PY - 2007 DA - 2007// TI - SIRT1 regulates the function of the Nijmegen breakage syndrome protein JO - Mol Cell VL - 27 ID - Yuan2007 ER - TY - JOUR AU - Wang, R. H. AU - Sengupta, K. AU - Li, C. AU - Kim, H. S. AU - Cao, L. AU - Xiao, C. PY - 2008 DA - 2008// TI - Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice JO - Cancer Cell VL - 14 ID - Wang2008 ER - TY - JOUR AU - Kang, H. AU - Jung, J. W. AU - Kim, M. K. AU - Chung, J. H. PY - 2009 DA - 2009// TI - CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage JO - PLoS One VL - 4 ID - Kang2009 ER - TY - JOUR AU - Liu, X. AU - Wang, D. AU - Zhao, Y. AU - Tu, B. AU - Zheng, Z. AU - Wang, L. AU - Wang, H. AU - Gu, W. AU - Roeder, R. G. AU - Zhu, W. G. PY - 2011 DA - 2011// TI - Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1) JO - Proc Natl Acad Sci USA VL - 108 ID - Liu2011 ER - TY - JOUR AU - Fan, W. AU - Luo, J. PY - 2010 DA - 2010// TI - SIRT1 regulates UV-induced DNA repair through deacetylating XPA JO - Mol Cell VL - 39 ID - Fan2010 ER - TY - JOUR AU - Ming, M. AU - Shea, C. R. AU - Guo, X. AU - Li, X. AU - Soltani, K. AU - Han, W. AU - He, Y. Y. PY - 2010 DA - 2010// TI - Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C JO - Proc Natl Acad Sci USA VL - 107 ID - Ming2010 ER - TY - JOUR AU - Scher, M. B. AU - Vaquero, A. AU - Reinberg, D. PY - 2007 DA - 2007// TI - SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress JO - Genes Dev VL - 21 ID - Scher2007 ER - TY - JOUR AU - Someya, S. AU - Yu, W. AU - Hallows, W. C. AU - Xu, J. AU - Vann, J. M. AU - Leeuwenburgh, C. AU - Tanokura, M. AU - Denu, J. M. AU - Prolla, T. A. PY - 2010 DA - 2010// TI - Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction JO - Cell VL - 143 ID - Someya2010 ER - TY - JOUR AU - Schwer, B. AU - Schumacher, B. AU - Lombard, D. B. AU - Xiao, C. AU - Kurtev, M. V. AU - Gao, J. AU - Schneider, J. I. AU - Chai, H. AU - Bronson, R. T. AU - Tsai, L. H. AU - Deng, C. X. AU - Alt, F. W. PY - 2010 DA - 2010// TI - Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity JO - Proc Natl Acad Sci USA VL - 107 ID - Schwer2010 ER - TY - JOUR AU - McCord, R. A. AU - Michishita, E. AU - Hong, T. AU - Berber, E. AU - Boxer, L. D. AU - Kusumoto, R. PY - 2009 DA - 2009// TI - SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair JO - Aging VL - 1 ID - McCord2009 ER - TY - JOUR AU - Kazantsev, A. G. AU - Thompson, L. M. PY - 2008 DA - 2008// TI - Therapeutic application of histone deacetylase inhibitors for central nervous system disorders JO - Nat Rev Drug Discov VL - 7 ID - Kazantsev2008 ER - TY - JOUR AU - Sekhavat, A. AU - Sun, J. M. AU - Davie, J. R. PY - 2007 DA - 2007// TI - Competitive inhibition of histone deacetylase activity by trichostatin A and butyrate JO - Biochem Cell Biol VL - 85 ID - Sekhavat2007 ER - TY - JOUR AU - Krämer, O. H. AU - Zhu, P. AU - Ostendorff, H. P. AU - Golebiewski, M. AU - Tiefenbach, J. AU - Peters, M. A. AU - Brill, B. AU - Groner, B. AU - Bach, I. AU - Heinzel, T. AU - Göttlicher, M. PY - 2003 DA - 2003// TI - The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2 JO - EMBO J VL - 22 ID - Krämer2003 ER - TY - JOUR AU - Doyle, K. AU - Fitzpatrick, F. A. PY - 2010 DA - 2010// TI - Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function JO - J Biol Chem VL - 285 ID - Doyle2010 ER - TY - JOUR AU - Caito, S. AU - Rajendrasozhan, S. AU - Cook, S. AU - Chung, S. AU - Yao, H. AU - Friedman, A. E. AU - Brookes, P. S. AU - Rahman, I. PY - 2010 DA - 2010// TI - SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress JO - FASEB J VL - 24 ID - Caito2010 ER - TY - JOUR AU - Chen, C. S. AU - Wang, Y. C. AU - Yang, H. C. AU - Huang, P. H. AU - Kulp, S. K. AU - Yang, C. C. AU - Lu, Y. S. AU - Matsuyama, S. AU - Chen, C. Y. AU - Chen, C. S. PY - 2007 DA - 2007// TI - Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation JO - Cancer Res VL - 67 ID - Chen2007 ER - TY - JOUR AU - Zhang, Y. AU - Carr, T. AU - Dimtchev, A. AU - Zaer, N. AU - Dritschilo, A. AU - Jung, M. PY - 2007 DA - 2007// TI - Attenuated DNA damage repair by trichostatin A through BRCA1 suppression JO - Radiat Res VL - 168 ID - Zhang2007 ER - TY - JOUR AU - Adimoolam, S. AU - Sirisawad, M. AU - Chen, J. AU - Thiemann, P. AU - Ford, J. M. AU - Buggy, J. J. PY - 2007 DA - 2007// TI - HDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombination JO - Proc Natl Acad Sci USA VL - 104 ID - Adimoolam2007 ER - TY - JOUR AU - Xu, W. S. AU - Parmigiani, R. B. AU - Marks, P. A. PY - 2007 DA - 2007// TI - Histone deacetylase inhibitors: molecular mechanisms of action JO - Oncogene VL - 26 ID - Xu2007 ER - TY - JOUR AU - Johnstone, R. W. AU - Licht, J. D. PY - 2003 DA - 2003// TI - Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? JO - Cancer Cell VL - 4 ID - Johnstone2003 ER - TY - JOUR AU - Taddei, A. AU - Roche, D. AU - Bickmore, W. A. AU - Almouzni, G. PY - 2005 DA - 2005// TI - The effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy? JO - EMBO Rep VL - 6 ID - Taddei2005 ER - TY - JOUR AU - Zain, J. AU - Kaminetzky, D. AU - O'Connor, O. A. PY - 2010 DA - 2010// TI - Emerging role of epigenetic therapies in cutaneous T-cell lymphomas JO - Expert Rev Hematol VL - 3 ID - Zain2010 ER - TY - JOUR AU - Palmieri, D. AU - Lockman, P. R. AU - Thomas, F. C. AU - Hua, E. AU - Herring, J. AU - Hargrave, E. AU - Johnson, M. PY - 2009 DA - 2009// TI - Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks JO - Clin Cancer Res VL - 15 ID - Palmieri2009 ER - TY - JOUR AU - Chen, G. AU - Li, A. AU - Zhao, M. AU - Gao, Y. AU - Zhou, T. AU - Xu, Y. AU - Du, Z. AU - Zhang, X. AU - Yu, X. PY - 2008 DA - 2008// TI - Proteomic analysis identifies protein targets responsible for depsipeptide sensitivity in tumor cells JO - J Proteome Res VL - 7 ID - Chen2008 ER - TY - JOUR AU - Rosato, R. R. AU - Almenara, J. A. AU - Maggio, S. C. AU - Coe, S. AU - Atadja, P. AU - Dent, P. AU - Grant, S. PY - 2008 DA - 2008// TI - Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions JO - Mol Cancer Ther VL - 7 ID - Rosato2008 ER - TY - JOUR AU - Dashwood, R. H. AU - Myzak, M. C. AU - Ho, E. PY - 2006 DA - 2006// TI - Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? JO - Carcinogenesis VL - 27 ID - Dashwood2006 ER - TY - JOUR AU - Dashwood, R. H. AU - Ho, E. PY - 2007 DA - 2007// TI - Dietary histone deacetylase inhibitors: from cells to mice to man JO - Semin Cancer Biol VL - 17 ID - Dashwood2007 ER - TY - JOUR AU - Higdon, J. V. AU - Delage, B. AU - Williams, D. E. AU - Dashwood, R. H. PY - 2007 DA - 2007// TI - Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis JO - Pharmacol Res VL - 55 ID - Higdon2007 ER - TY - JOUR AU - Hayes, J. D. AU - Kelleher, M. O. AU - Eggleston, I. M. PY - 2008 DA - 2008// TI - The cancer chemopreventive actions of phytochemicals derived from glucosinolates JO - Eur J Nutr VL - 47 ID - Hayes2008 ER - TY - JOUR AU - Myzak, M. C. AU - Karplus, P. A. AU - Chung, F. L. AU - Dashwood, R. H. PY - 2004 DA - 2004// TI - A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase JO - Cancer Res VL - 64 ID - Myzak2004 ER - TY - JOUR AU - Lea, M. A. AU - Randolph, V. M. AU - Lee, J. E. AU - desBordes, C. PY - 2001 DA - 2001// TI - Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate JO - Int J Cancer VL - 92 ID - Lea2001 ER - TY - JOUR AU - Batra, S. AU - Sahu, R. P. AU - Kandala, P. K. AU - Srivastava, S. K. PY - 2010 DA - 2010// TI - Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells JO - Mol Cancer Ther VL - 9 ID - Batra2010 ER - TY - JOUR AU - Ma, X. AU - Fang, Y. AU - Beklemisheva, A. AU - Dai, W. AU - Feng, J. AU - Ahmed, T. AU - Liu, D. AU - Chiao, J. W. PY - 2006 DA - 2006// TI - Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells JO - Int J Oncol VL - 28 ID - Ma2006 ER - TY - JOUR AU - Wang, L. G. AU - Liu, X. M. AU - Fang, Y. AU - Dai, W. AU - Chiao, F. B. AU - Puccio, G. M. AU - Feng, J. AU - Liu, D. AU - Chiao, J. W. PY - 2008 DA - 2008// TI - De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc JO - Int J Oncol VL - 33 ID - Wang2008 ER - TY - JOUR AU - Meeran, S. M. AU - Patel, S. N. AU - Tollefsbol, T. O. PY - 2010 DA - 2010// TI - Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines JO - PLoS One VL - 5 ID - Meeran2010 ER - TY - JOUR AU - Rajendran, P. AU - Delage, B. AU - Dashwood, W. M. AU - Yu, T. W. AU - Wuth, B. AU - Williams, D. E. AU - Ho, E. AU - Dashwood, R. H. PY - 2011 DA - 2011// TI - Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly JO - Mol Cancer VL - 10 ID - Rajendran2011 ER - TY - CHAP AU - Clarke, J. D. AU - Hsu, A. AU - Yu, Z. AU - Dashwood, R. H. AU - Ho, E. PY - 2011 DA - 2011// TI - Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells BT - Mol Nutr Food Res ID - Clarke2011 ER - TY - JOUR AU - Kassie, F. AU - Laky, B. AU - Nobis, E. AU - Kundi, M. AU - Knasmüller, S. PY - 2001 DA - 2001// TI - Genotoxic effects of methyl isothiocyanate JO - Mutat Res VL - 490 ID - Kassie2001 ER - TY - JOUR AU - Kassie, F. AU - Pool-Zobel, B. AU - Parzefall, W. AU - Knasmüller, S. PY - 1999 DA - 1999// TI - Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent JO - Mutagenesis VL - 14 ID - Kassie1999 ER - TY - JOUR AU - Kassie, F. AU - Knasmüller, S. PY - 2000 DA - 2000// TI - Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC) JO - Chem-Biol Interact VL - 127 ID - Kassie2000 ER - TY - JOUR AU - Zhang, R. AU - Loganathan, S. AU - Humphreys, I. AU - Srivastava, S. K. PY - 2006 DA - 2006// TI - Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells JO - J Nutr VL - 136 ID - Zhang2006 ER - TY - JOUR AU - Sekine-Suzuki, E. AU - Yu, D. AU - Kubota, N. AU - Okayasu, R. AU - Anzai, K. PY - 2008 DA - 2008// TI - Sulforaphane induces DNA double strand breaks predominantly repaired by homologous recombination pathway in human cancer cells JO - Biochem Biophys Res Commun VL - 377 ID - Sekine-Suzuki2008 ER - TY - JOUR AU - Sestili, P. AU - Paolillo, M. AU - Lenzi, M. AU - Colombo, E. AU - Vallorani, L. AU - Casadei, L. AU - Martinelli, C. AU - Fimognari, C. PY - 2010 DA - 2010// TI - Sulforaphane induces DNA single strand breaks in cultured human cells JO - Mutat Res VL - 689 ID - Sestili2010 ER - TY - JOUR AU - Andelová, H. AU - Rudolf, E. AU - Cervinka, M. PY - 2007 DA - 2007// TI - In vitro antiproliferative effects of sulforaphane on human colon cancer cell line SW620 JO - Acta Medica (Hradec Kralove) VL - 50 ID - Andelová2007 ER - TY - JOUR AU - Singh, S. V. AU - Herman-Antosiewicz, A. AU - Singh, A. V. AU - Lew, K. L. AU - Srivastava, S. K. AU - Kamath, R. AU - Brown, K. D. AU - Zhang, L. AU - Baskaran, R. PY - 2004 DA - 2004// TI - Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C JO - J Biol Chem VL - 279 ID - Singh2004 ER - TY - JOUR AU - Zeng, H. AU - Trujillo, O. N. AU - Moyer, M. P. AU - Botnen, J. H. PY - 2011 DA - 2011// TI - Prolonged sulforaphane treatment activates survival signaling in nontumorigenic NCM460 colon cells but apoptotic signaling in tumorigenic HCT116 colon cells JO - Nutr Cancer VL - 63 ID - Zeng2011 ER - TY - JOUR AU - Xiao, D. AU - Powolny, A. A. AU - Antosiewicz, J. AU - Hahm, E. R. AU - Bommareddy, A. AU - Zeng, Y. AU - Desai, D. AU - Amin, S. AU - Herman-Antosiewicz, A. AU - Singh, S. V. PY - 2009 DA - 2009// TI - Cellular responses to cancer chemopreventive agent D, L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species JO - Pharm Res VL - 26 ID - Xiao2009 ER - TY - JOUR AU - Xiao, D. AU - Powolny, A. A. AU - Moura, M. B. AU - Kelley, E. E. AU - Bommareddy, A. AU - Kim, S. H. AU - Hahm, E. R. AU - Normolle, D. AU - Van Houten, B. AU - Singh, S. V. PY - 2010 DA - 2010// TI - Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells JO - J Biol Chem VL - 285 ID - Xiao2010 ER - TY - JOUR AU - Powolny, A. A. AU - Singh, S. V. PY - 2010 DA - 2010// TI - Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes JO - Pharm Res VL - 27 ID - Powolny2010 ER - TY - JOUR AU - Liu, K. C. AU - Huang, Y. T. AU - Wu, P. P. AU - Ji, B. C. AU - Yang, J. S. PY - 2011 DA - 2011// TI - The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway JO - Int J Oncol VL - 38 ID - Liu2011 ER - TY - JOUR AU - Moon, D. O. AU - Kang, S. H. AU - Kim, K. C. AU - Kim, M. O. AU - Choi, Y. H. AU - Kim, G. Y. PY - 2010 DA - 2010// TI - Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway JO - Cancer Lett VL - 295 ID - Moon2010 ER - TY - JOUR AU - Sharma, R. AU - Sharma, A. AU - Chaudhary, P. AU - Pearce, V. AU - Vatsyayan, R. AU - Singh, S. V. AU - Awasthi, S. AU - Awasthi, Y. C. PY - 2010 DA - 2010// TI - Role of lipid peroxidation in cellular responses to D, L-sulforaphane, a promising cancer chemopreventive agent JO - Biochemistry VL - 49 ID - Sharma2010 ER - TY - JOUR AU - Mi, L. AU - Chung, F. L. PY - 2008 DA - 2008// TI - Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells JO - Nutr Cancer VL - 60 ID - Mi2008 ER - TY - JOUR AU - Ahmad, A. AU - Sakr, W. A. AU - Rahman, K. M. PY - 2010 DA - 2010// TI - Anticancer properties of indole compounds: mechanism of apoptosis induction and role in chemotherapy JO - Curr Drug Targets VL - 11 ID - Ahmad2010 ER - TY - JOUR AU - Brew, C. T. AU - Aronchik, I. AU - Hsu, J. C. AU - Sheen, J. H. AU - Dickson, R. B. AU - Bjeldanes, L. F. AU - Firestone, G. L. PY - 2006 DA - 2006// TI - Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells JO - Int J Cancer VL - 118 ID - Brew2006 ER - TY - JOUR AU - Wu, Y. AU - Feng, X. AU - Jin, Y. AU - Wu, Z. AU - Hankey, W. AU - Paisie, C. AU - Li, L. AU - Liu, F. AU - Barsky, S. H. AU - Zhang, W. AU - Ganju, R. AU - Zou, X. PY - 2010 DA - 2010// TI - A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradation JO - Cancer Prev Res VL - 3 ID - Wu2010 ER - TY - JOUR AU - Bhatnagar, N. AU - Li, X. AU - Chen, Y. AU - Zhou, X. AU - Garrett, S. H. AU - Guo, B. PY - 2009 DA - 2009// TI - 3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin JO - Cancer Prev Res VL - 2 ID - Bhatnagar2009 ER - TY - JOUR AU - Li, Y. AU - Li, X. AU - Guo, B. PY - 2010 DA - 2010// TI - Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases JO - Cancer Res VL - 70 ID - Li2010 ER - TY - JOUR AU - Fan, S. AU - Meng, Q. AU - Auborn, K. AU - Carter, T. AU - Rosen, E. M. PY - 2006 DA - 2006// TI - BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells JO - Br J Cancer VL - 94 ID - Fan2006 ER - TY - JOUR AU - Auborn, K. J. AU - Fan, S. AU - Rosen, E. M. AU - Goodwin, L. AU - Chandraskaren, A. AU - Williams, D. E. AU - Chen, D. AU - Carter, T. H. PY - 2003 DA - 2003// TI - Indole-3-carbinol is a negative regulator of estrogen JO - J Nutr VL - 133 ID - Auborn2003 ER - TY - JOUR AU - Pajak, B. AU - Gajkowska, B. AU - Orzechowski, A. PY - 2008 DA - 2008// TI - Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells JO - Folia Histochem Cytobiol VL - 46 ID - Pajak2008 ER - TY - JOUR AU - Gopal, Y. N. AU - Arora, T. S. AU - Van Dyke, M. W. PY - 2007 DA - 2007// TI - Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasia mutated JO - Chem Biol VL - 14 ID - Gopal2007 ER - TY - JOUR AU - Gopal, Y. N. AU - Chanchorn, E. AU - Van Dyke, M. W. PY - 2009 DA - 2009// TI - Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions JO - Mol Cancer Ther VL - 8 ID - Gopal2009 ER - TY - JOUR AU - Balasubramanyam, K. AU - Swaminathan, V. AU - Ranganathan, A. AU - Kundu, T. K. PY - 2003 DA - 2003// TI - Small molecule modulators of histone acetyltransferase p300 JO - J Biol Chem VL - 278 ID - Balasubramanyam2003 ER - TY - JOUR AU - Sun, Y. AU - Jiang, X. AU - Chen, S. AU - Price, B. D. PY - 2006 DA - 2006// TI - Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation JO - FEBS Lett VL - 580 ID - Sun2006 ER - TY - JOUR AU - Ruotolo, R. AU - Tosi, F. AU - Vernarecci, S. AU - Ballario, P. AU - Mai, A. AU - Filetici, P. AU - Ottonello, S. PY - 2010 DA - 2010// TI - Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound JO - Genomics VL - 96 ID - Ruotolo2010 ER - TY - JOUR AU - Kim, M. K. AU - Shin, J. M. AU - Eun, H. C. AU - Chung, J. H. PY - 2009 DA - 2009// TI - The role of p300 histone acetyltransferase in UV-induced histone modifications and MMP-1 gene transcription JO - PLoS One VL - 4 ID - Kim2009 ER - TY - JOUR AU - Iciek, M. AU - Kwiecień, I. AU - Włodek, L. PY - 2009 DA - 2009// TI - Biological properties of garlic and garlic-derived organosulfur compounds JO - Environ Mol Mutagen VL - 50 ID - Iciek2009 ER - TY - JOUR AU - Nian, H. AU - Delage, B. AU - Ho, E. AU - Dashwood, R. H. PY - 2009 DA - 2009// TI - Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds JO - Environ Mol Mutagen VL - 50 ID - Nian2009 ER - TY - JOUR AU - Lea, M. A. AU - Randolph, V. M. AU - Patel, M. PY - 1999 DA - 1999// TI - Increased acetylation of histones induced by diallyl disulfide and structurally related molecules JO - Int J Oncol VL - 15 ID - Lea1999 ER - TY - JOUR AU - Lea, M. A. AU - Randolph, V. M. PY - 2001 DA - 2001// TI - Induction of histone acetylation in rat liver and hepatoma by organosulfur compounds including diallyl disulfide JO - Anticancer Res VL - 21 ID - Lea2001 ER - TY - JOUR AU - Lea, M. A. AU - Rasheed, M. AU - Randolph, V. M. AU - Khan, F. AU - Shareef, A. AU - desBordes, C. PY - 2002 DA - 2002// TI - Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine JO - Nutr Cancer VL - 43 ID - Lea2002 ER - TY - JOUR AU - Nian, H. AU - Delage, B. AU - Pinto, J. T. AU - Dashwood, R. H. PY - 2008 DA - 2008// TI - Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter JO - Carcinogenesis VL - 29 ID - Nian2008 ER - TY - JOUR AU - Wang, H. C. AU - Yang, J. H. AU - Hsieh, S. C. AU - Sheen, L. Y. PY - 2010 DA - 2010// TI - Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis JO - J Agric Food Chem VL - 58 ID - Wang2010 ER - TY - JOUR AU - Ling, H. AU - Wen, L. AU - Ji, X. X. AU - Tang, Y. L. AU - He, J. AU - Tan, H. AU - Xia, H. AU - Zhou, J. G. AU - Su, Q. PY - 2010 DA - 2010// TI - Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide JO - Braz J Med Biol Res VL - 43 ID - Ling2010 ER - TY - JOUR AU - Herman-Antosiewicz, A. AU - Singh, S. V. PY - 2005 DA - 2005// TI - Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells JO - J Biol Chem VL - 280 ID - Herman-Antosiewicz2005 ER - TY - JOUR AU - Wang, H. AU - Zhao, Y. AU - Li, L. AU - McNutt, M. A. AU - Wu, L. AU - Lu, S. AU - Yu, Y. AU - Zhou, W. AU - Feng, J. AU - Chai, G. AU - Yang, Y. AU - Zhu, W. G. PY - 2008 DA - 2008// TI - An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment JO - J Biol Chem VL - 283 ID - Wang2008 ER - TY - JOUR AU - Konkimalla, V. S. AU - Wang, G. AU - Kaina, B. AU - Efferth, T. PY - 2008 DA - 2008// TI - Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine JO - Cancer Genomics Proteomics VL - 5 ID - Konkimalla2008 ER - TY - JOUR AU - Yi, L. AU - Ji, X. X. AU - Lin, M. AU - Tan, H. AU - Tang, Y. AU - Wen, L. AU - Ma, Y. H. AU - Su, Q. PY - 2010 DA - 2010// TI - Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen JO - Pharmazie VL - 65 ID - Yi2010 ER - TY - JOUR AU - Aquilano, K. AU - Filomeni, G. AU - Baldelli, S. AU - Piccirillo, S. AU - De Martino, A. AU - Rotilio, G. AU - Ciriolo, M. R. PY - 2007 DA - 2007// TI - Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives JO - J Neurochem VL - 101 ID - Aquilano2007 ER - TY - JOUR AU - Lu, H. F. AU - Sue, C. C. AU - Yu, C. S. AU - Chen, S. C. AU - Chen, G. W. AU - Chung, J. G. PY - 2004 DA - 2004// TI - Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells JO - Food Chem Toxicol VL - 42 ID - Lu2004 ER - TY - JOUR AU - Sriram, N. AU - Kalayarasan, S. AU - Ashokkumar, P. AU - Sureshkumar, A. AU - Sudhandiran, G. PY - 2008 DA - 2008// TI - Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-kappaB, and ERK-2 JO - Mol Cell Biochem VL - 311 ID - Sriram2008 ER - TY - JOUR AU - Hatfield, D. L. AU - Yoo, M. H. AU - Carlson, B. A. AU - Gladyshev, V. N. PY - 2009 DA - 2009// TI - Selenoproteins that function in cancer prevention and promotion JO - Biochim Biophys Acta VL - 1790 ID - Hatfield2009 ER - TY - JOUR AU - Zeng, H. AU - Combs, G. F. PY - 2008 DA - 2008// TI - Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion JO - J Nutr Biochem VL - 19 ID - Zeng2008 ER - TY - JOUR AU - Clark, L. C. AU - Combs, G. F. AU - Turnbull, B. W. AU - Slate, E. H. AU - Chalker, D. K. AU - Chow, J. AU - Davis, L. S. PY - 1996 DA - 1996// TI - Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group JO - JAMA VL - 276 ID - Clark1996 ER - TY - JOUR AU - Sanmartín, C. AU - Plano, D. AU - Palop, J. A. PY - 2008 DA - 2008// TI - Selenium compounds and apoptotic modulation: a new perspective in cancer therapy JO - Mini Rev Med Chem VL - 8 ID - Sanmartín2008 ER - TY - JOUR AU - Xiang, N. AU - Zhao, R. AU - Song, G. AU - Zhong, W. PY - 2008 DA - 2008// TI - Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells JO - Carcinogenesis VL - 29 ID - Xiang2008 ER - TY - JOUR AU - Lee, J. I. AU - Nian, H. AU - Cooper, A. J. AU - Sinha, R. AU - Dai, J. AU - Bisson, W. H. AU - Dashwood, R. H. AU - Pinto, J. T. PY - 2009 DA - 2009// TI - Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells JO - Cancer Prev Res VL - 2 ID - Lee2009 ER - TY - JOUR AU - Nian, H. AU - Bisson, W. H. AU - Dashwood, W. M. AU - Pinto, J. T. AU - Dashwood, R. H. PY - 2009 DA - 2009// TI - Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells JO - Carcinogenesis VL - 30 ID - Nian2009 ER - TY - JOUR AU - Goulet, A. C. AU - Watts, G. AU - Lord, J. L. AU - Nelson, M. A. PY - 2007 DA - 2007// TI - Profiling of selenomethionine responsive genes in colon cancer by microarray analysis JO - Cancer Biol Ther VL - 6 ID - Goulet2007 ER - TY - JOUR AU - Zhou, N. AU - Xiao, H. AU - Li, T. K. AU - Nur-E-Kamal, A. AU - Liu, L. F. PY - 2003 DA - 2003// TI - DNA damage-mediated apoptosis induced by selenium compounds JO - J Biol Chem VL - 278 ID - Zhou2003 ER - TY - JOUR AU - Qi, Y. AU - Schoene, N. W. AU - Lartey, F. M. AU - Cheng, W. H. PY - 2010 DA - 2010// TI - Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells JO - J Biol Chem VL - 285 ID - Qi2010 ER - TY - JOUR AU - Wu, M. AU - Kang, M. M. AU - Schoene, N. W. AU - Cheng, W. H. PY - 2010 DA - 2010// TI - Selenium compounds activate early barriers of tumorigenesis JO - J Biol Chem VL - 285 ID - Wu2010 ER - TY - JOUR AU - Lee, J. S. PY - 2007 DA - 2007// TI - Functional link between DNA damage responses and transcriptional regulation by ATM in response to a histone deacetylase inhibitor TSA JO - Cancer Res Treat VL - 39 ID - Lee2007 ER - TY - JOUR AU - Kato, M. A. AU - Finley, D. J. AU - Lubitz, C. C. AU - Zhu, B. AU - Moo, T. A. AU - Loeven, M. R. AU - Ricci, J. A. AU - Zarnegar, R. AU - Katdare, M. AU - Fahey, T. J. PY - 2010 DA - 2010// TI - Selenium decreases thyroid cancer cell growth by increasing expression of GADD153 and GADD34 JO - Nutr Cancer VL - 62 ID - Kato2010 ER - TY - JOUR AU - Jiang, W. AU - Jiang, C. AU - Pei, H. AU - Wang, L. AU - Zhang, J. AU - Hu, H. AU - Lü, J. PY - 2009 DA - 2009// TI - In vivo molecular mediators of cancer growth suppression and apoptosis by selenium in mammary and prostate models: lack of involvement of gadd genes JO - Mol Cancer Ther VL - 8 ID - Jiang2009 ER - TY - JOUR AU - Chen, T. AU - Wong, Y. S. PY - 2009 DA - 2009// TI - Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cells JO - Biomed Pharmacother VL - 63 ID - Chen2009 ER - TY - JOUR AU - Kotsopoulos, J. AU - Chen, Z. AU - Vallis, K. A. AU - Poll, A. AU - Ghadirian, P. AU - Kennedy, G. AU - Ainsworth, P. AU - Narod, S. A. PY - 2010 DA - 2010// TI - Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers JO - Cancer Causes Control VL - 21 ID - Kotsopoulos2010 ER - TY - JOUR AU - Katiyar, S. AU - Elmets, C. A. AU - Katiyar, S. K. PY - 2007 DA - 2007// TI - Green tea and skin cancer: photoimmunology, angiogenesis and DNA repair JO - J Nutr Biochem VL - 18 ID - Katiyar2007 ER - TY - JOUR AU - Pandey, M. AU - Shukla, S. AU - Gupta, S. PY - 2010 DA - 2010// TI - Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells JO - Int J Cancer VL - 126 ID - Pandey2010 ER - TY - JOUR AU - Nandakumar, V. AU - Vaid, M. AU - Katiyar, S. K. PY - 2011 DA - 2011// TI - (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells JO - Carcinogenesis VL - 32 ID - Nandakumar2011 ER - TY - JOUR AU - Li, Y. AU - Yuan, Y. Y. AU - Meeran, S. M. AU - Tollefsbol, T. O. PY - 2010 DA - 2010// TI - Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells JO - Mol Cancer VL - 9 ID - Li2010 ER - TY - JOUR AU - Choi, K. C. AU - Jung, M. G. AU - Lee, Y. H. AU - Yoon, J. C. AU - Kwon, S. H. AU - Kang, H. B. PY - 2009 DA - 2009// TI - Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation JO - Cancer Res VL - 69 ID - Choi2009 ER - TY - JOUR AU - Balasubramanian, S. AU - Adhikary, G. AU - Eckert, R. L. PY - 2010 DA - 2010// TI - The Bmi-1 polycomb protein antagonizes the (-)-Epigallocatechin-3-Gallate dependent suppression of skin cancer cell survival JO - Carcinogenesis VL - 31 ID - Balasubramanian2010 ER - TY - JOUR AU - Delage, B. AU - Dashwood, R. H. PY - 2008 DA - 2008// TI - Dietary manipulation of histone structure and function JO - Annu Rev Nutr VL - 28 ID - Delage2008 ER - TY - JOUR AU - Li, G. X. AU - Chen, Y. K. AU - Hou, Z. AU - Xiao, H. AU - Jin, H. AU - Lu, G. AU - Lee, M. J. AU - Liu, B. AU - Guan, F. AU - Yang, Z. AU - Yu, A. AU - Yang, C. S. PY - 2010 DA - 2010// TI - Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro JO - Carcinogenesis VL - 31 ID - Li2010 ER - TY - JOUR AU - Suganuma, M. AU - Saha, A. AU - Fujiki, H. PY - 2011 DA - 2011// TI - New cancer treatment strategy using combination of green tea catechins and anticancer drugs JO - Cancer Sci VL - 102 ID - Suganuma2011 ER - TY - JOUR AU - Kurland, J. F. AU - Tansey, W. P. PY - 2008 DA - 2008// TI - Myc-mediated transcriptional repression by recruitment of histone deacetylase JO - Cancer Res VL - 68 ID - Kurland2008 ER - TY - JOUR AU - Scuto, A. AU - Kirschbaum, M. AU - Kowolik, C. AU - Kretzner, L. AU - Juhasz, A. AU - Atadja, P. AU - Pullarkat, V. AU - Bhatia, R. AU - Forman, S. AU - Yen, Y. AU - Jove, R. PY - 2008 DA - 2008// TI - The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells JO - Blood VL - 111 ID - Scuto2008 ER - TY - JOUR AU - Ahmad, K. A. AU - Harris, N. H. AU - Johnson, A. D. AU - Lindvall, H. C. AU - Wang, G. AU - Ahmed, K. PY - 2007 DA - 2007// TI - Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells JO - Mol Cancer Ther VL - 6 ID - Ahmad2007 ER - TY - JOUR AU - Fang, M. Z. AU - Wang, Y. AU - Ai, N. AU - Hou, Z. AU - Sun, Y. AU - Lu, H. PY - 2003 DA - 2003// TI - Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines JO - Cancer Res VL - 63 ID - Fang2003 ER - TY - JOUR AU - Lee, W. J. AU - Shim, J. Y. AU - Zhu, B. T. PY - 2005 DA - 2005// TI - Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids JO - Mol Pharmacol VL - 68 ID - Lee2005 ER - TY - JOUR AU - Wang, H. F. AU - Chuang, S. M. AU - Hsiao, C. C. AU - Cherng, S. H. PY - 2011 DA - 2011// TI - A synergistic effect of GABA tea and copper(II) on DNA breakage in human peripheral lymphocytes JO - Food Chem Toxicol VL - 49 ID - Wang2011 ER - TY - JOUR AU - Aggarwal, B. B. PY - 2010 DA - 2010// TI - Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals JO - Annu Rev Nutr VL - 30 ID - Aggarwal2010 ER - TY - JOUR AU - Padhye, S. AU - Chavan, D. AU - Pandey, S. AU - Deshpande, J. AU - Swamy, K. V. AU - Sarkar, F. H. PY - 2010 DA - 2010// TI - Perspectives on chemopreventive and therapeutic potential of curcumin analogs in medicinal chemistry JO - Mini Rev Med Chem VL - 10 ID - Padhye2010 ER - TY - JOUR AU - Bar-Sela, G. AU - Epelbaum, R. AU - Schaffer, M. PY - 2010 DA - 2010// TI - Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications JO - Curr Med Chem VL - 17 ID - Bar-Sela2010 ER - TY - JOUR AU - Epstein, J. AU - Sanderson, I. R. AU - Macdonald, T. T. PY - 2010 DA - 2010// TI - Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies JO - Br J Nutr VL - 103 ID - Epstein2010 ER - TY - JOUR AU - Fu, S. AU - Kurzrock, R. PY - 2010 DA - 2010// TI - Development of curcumin as an epigenetic agent JO - Cancer VL - 116 ID - Fu2010 ER - TY - JOUR AU - Chung, S. AU - Yao, H. AU - Caito, S. AU - Hwang, J. W. AU - Arunachalam, G. AU - Rahman, I. PY - 2010 DA - 2010// TI - Regulation of SIRT1 in cellular functions: role of polyphenols JO - Arch Biochem Biophys VL - 501 ID - Chung2010 ER - TY - JOUR AU - Li, Y. AU - Kong, D. AU - Wang, Z. AU - Sarkar, F. H. PY - 2010 DA - 2010// TI - Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research JO - Pharm Res VL - 27 ID - Li2010 ER - TY - JOUR AU - Marcu, M. G. AU - Jung, Y. J. AU - Lee, S. AU - Chung, E. J. AU - Lee, M. J. AU - Trepel, J. AU - Neckers, L. PY - 2006 DA - 2006// TI - Curcumin is an inhibitor of p300 histone acetylatransferase JO - Med Chem VL - 2 ID - Marcu2006 ER - TY - JOUR AU - Balasubramanyam, K. AU - Varier, R. A. AU - Altaf, M. AU - Swaminathan, V. AU - Siddappa, N. B. AU - Ranga, U. PY - 2004 DA - 2004// TI - Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription JO - J Biol Chem VL - 279 ID - Balasubramanyam2004 ER - TY - JOUR AU - Kang, J. AU - Chen, J. AU - Shi, Y. AU - Jia, J. AU - Zhang, Y. PY - 2005 DA - 2005// TI - Curcumin-induced histone hypoacetylation: the role of reactive oxygen species JO - Biochem Pharmacol VL - 69 ID - Kang2005 ER - TY - JOUR AU - Mai, A. AU - Rotili, D. AU - Tarantino, D. AU - Ornaghi, P. AU - Tosi, F. AU - Vicidomini, C. PY - 2006 DA - 2006// TI - Small molecule inhibitors of histone acetyltransferase activity: identification and biological properties JO - J Med Chem VL - 49 ID - Mai2006 ER - TY - JOUR AU - Lv, B. H. AU - Zhang, L. AU - Zhu, C. C. AU - Liu, J. PY - 2007 DA - 2007// TI - Inhibition of curcumin on histone deacetylase and expression promotion of P21 (WAF1/CIP1) in HepG2 cells JO - Zhongguo Zhong Yao Za Zhi VL - 32 ID - Lv2007 ER - TY - JOUR AU - Chen, Y. AU - Shu, W. AU - Chen, W. AU - Wu, Q. AU - Liu, H. AU - Cui, G. PY - 2007 DA - 2007// TI - Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells JO - Basic Clin Pharmacol Toxicol VL - 101 ID - Chen2007 ER - TY - JOUR AU - Bora-Tatar, G. AU - Dayangac-Erden, D. AU - Demir, A. S. AU - Dalkara, S. AU - Yelekci, K. AU - Erdem-Yurter, H. PY - 2009 DA - 2009// TI - Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies JO - Bioorg Med Chem VL - 17 ID - Bora-Tatar2009 ER - TY - JOUR AU - Meja, K. K. AU - Rajendrasozhan, S. AU - Adenuga, D. AU - Biswas, S. K. AU - Sundar, I. K. PY - 2008 DA - 2008// TI - Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2 JO - Am J Respir Cell Mol Biol VL - 39 ID - Meja2008 ER - TY - JOUR AU - Rowe, D. L. AU - Ozbay, T. AU - O'Regan, R. M. AU - Nahta, R. PY - 2009 DA - 2009// TI - Modulation of the BRCA1 protein and induction of apoptosis in triple negative breast cancer cell lines by the polyphenolic compound Curcumin JO - Breast Cancer (Auckl) VL - 3 ID - Rowe2009 ER - TY - JOUR AU - Sahu, R. P. AU - Batra, S. AU - Srivastava, S. K. PY - 2009 DA - 2009// TI - Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells JO - Br J Cancer VL - 100 ID - Sahu2009 ER - TY - JOUR AU - Saha, A. AU - Kuzuhara, T. AU - Echigo, N. AU - Fujii, A. AU - Suganuma, M. AU - Fujiki, H. PY - 2010 DA - 2010// TI - Apoptosis of human lung cancer cells by curcumin mediated through up-regulation of growth arrest and DNA damage inducible genes 45 and 153 JO - Biol Pharm Bull VL - 33 ID - Saha2010 ER - TY - JOUR AU - Lin, S. S. AU - Huang, H. P. AU - Yang, J. S. AU - Wu, J. Y. AU - Hsia, T. C. PY - 2008 DA - 2008// TI - DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway JO - Cancer Lett VL - 272 ID - Lin2008 ER - TY - JOUR AU - Sun, Y. AU - Jiang, X. AU - Chen, S. AU - Fernandes, N. AU - Price, B. D. PY - 2005 DA - 2005// TI - A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM JO - Proc Natl Acad Sci USA VL - 102 ID - Sun2005 ER - TY - JOUR AU - Chirnomas, D. AU - Taniguchi, T. AU - de la Vega, M. AU - Vaidya, A. P. AU - Vasserman, M. PY - 2006 DA - 2006// TI - Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway JO - Mol Cancer Ther VL - 5 ID - Chirnomas2006 ER - TY - JOUR AU - Dhandapani, K. M. AU - Mahesh, V. B. AU - Brann, D. W. PY - 2007 DA - 2007// TI - Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors JO - J Neurochem VL - 102 ID - Dhandapani2007 ER - TY - JOUR AU - Cao, J. AU - Liu, Y. AU - Jia, L. AU - Zhou, H. M. AU - Kong, Y. AU - Yang, G. AU - Jiang, L. P. AU - Li, Q. J. AU - Zhong, L. F. PY - 2007 DA - 2007// TI - Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells JO - Free Radic Biol Med VL - 43 ID - Cao2007 ER - TY - JOUR AU - Hail, N. PY - 2008 DA - 2008// TI - Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis JO - Free Radic Biol Med VL - 44 ID - Hail2008 ER - TY - JOUR AU - Hilchie, A. L. AU - Furlong, S. J. AU - Sutton, K. AU - Richardson, A. AU - Robichaud, M. R. AU - Giacomantonio, C. A. AU - Ridgway, N. D. AU - Hoskin, D. W. PY - 2010 DA - 2010// TI - Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria JO - Nutr Cancer VL - 62 ID - Hilchie2010 ER - TY - JOUR AU - Athar, M. AU - Back, J. H. AU - Kopelovich, L. AU - Bickers, D. R. AU - Kim, A. L. PY - 2009 DA - 2009// TI - Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms JO - Arch Biochem Biophys VL - 486 ID - Athar2009 ER - TY - JOUR AU - Howitz, K. T. AU - Bitterman, K. J. AU - Cohen, H. Y. AU - Lamming, D. W. AU - Lavu, S. AU - Wood, J. G. PY - 2003 DA - 2003// TI - Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan JO - Nature VL - 425 ID - Howitz2003 ER - TY - JOUR AU - Wood, J. G. AU - Rogina, B. AU - Lavu, S. AU - Howitz, K. AU - Helfand, S. L. AU - Tatar, M. PY - 2004 DA - 2004// TI - Sirtuin activators mimic caloric restriction and delay ageing in metazoans JO - Nature VL - 430 ID - Wood2004 ER - TY - JOUR AU - Beher, D. AU - Wu, J. AU - Cumine, S. AU - Kim, K. W. AU - Lu, S. C. AU - Atangan, L. PY - 2009 DA - 2009// TI - Resveratrol is not a direct activator of SIRT1 enzyme activity JO - Chem Biol Drug Des VL - 74 ID - Beher2009 ER - TY - JOUR AU - Malik, R. AU - Kashyap, A. AU - Bansal, K. AU - Sharma, P. AU - Rayasam, G. V. AU - Davis, J. A. AU - Bora, R. S. AU - Ray, A. AU - Saini, K. S. PY - 2010 DA - 2010// TI - Comparative deacetylase activity of wild type and mutants of SIRT1 JO - Biochem Biophys Res Commun VL - 391 ID - Malik2010 ER - TY - JOUR AU - Boily, G. AU - He, X. H. AU - Pearce, B. AU - Jardine, K. AU - McBurney, M. W. PY - 2009 DA - 2009// TI - SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol JO - Oncogene VL - 28 ID - Boily2009 ER - TY - JOUR AU - Wang, R. H. AU - Zheng, Y. AU - Kim, H. S. AU - Xu, X. AU - Cao, L. AU - Luhasen, T. PY - 2008 DA - 2008// TI - Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis JO - Mol Cell VL - 32 ID - Wang2008 ER - TY - JOUR AU - Kai, L. AU - Samuel, S. K. AU - Levenson, A. S. PY - 2010 DA - 2010// TI - Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex JO - Int J Cancer VL - 126 ID - Kai2010 ER - TY - JOUR AU - Gatz, S. A. AU - Keimling, M. AU - Baumann, C. AU - Dörk, T. AU - Debatin, K. M. AU - Fulda, S. AU - Wiesmüller, L. PY - 2008 DA - 2008// TI - Resveratrol modulates DNA double-strand break repair pathways in an ATM/ATR-p53- and -Nbs1-dependent manner JO - Carcinogenesis VL - 29 ID - Gatz2008 ER - TY - JOUR AU - Leone, S. AU - Cornetta, T. AU - Basso, E. AU - Cozzi, R. PY - 2010 DA - 2010// TI - Resveratrol induces DNA double-strand breaks through human topoisomerase II interaction JO - Cancer Lett VL - 295 ID - Leone2010 ER - TY - JOUR AU - Rusin, M. AU - Zajkowicz, A. AU - Butkiewicz, D. PY - 2009 DA - 2009// TI - Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1 JO - Mech Ageing Dev VL - 130 ID - Rusin2009 ER - TY - JOUR AU - Tyagi, A. AU - Singh, R. P. AU - Agarwal, C. AU - Siriwardana, S. AU - Sclafani, R. A. AU - Agarwal, R. PY - 2005 DA - 2005// TI - Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells JO - Carcinogenesis VL - 26 ID - Tyagi2005 ER - TY - JOUR AU - Azmi, A. S. AU - Bhat, S. H. AU - Hadi, S. M. PY - 2005 DA - 2005// TI - Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: implications for anticancer properties JO - FEBS Lett VL - 579 ID - Azmi2005 ER - TY - JOUR AU - Hadi, S. M. AU - Ullah, M. F. AU - Azmi, A. S. AU - Ahmad, A. AU - Shamim, U. AU - Zubair, H. AU - Khan, H. Y. PY - 2010 DA - 2010// TI - Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer JO - Pharm Res VL - 27 ID - Hadi2010 ER - TY - JOUR AU - Kaur, M. AU - Agarwal, R. AU - Agarwal, C. PY - 2006 DA - 2006// TI - Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation JO - Mol Cancer Ther VL - 5 ID - Kaur2006 ER - TY - JOUR AU - Guha, P. AU - Dey, A. AU - Sen, R. AU - Chatterjee, M. AU - Chattopadhyay, S. AU - Bandyopadhyay, S. K. PY - 2011 DA - 2011// TI - Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line JO - J Pharmacol Exp Ther VL - 336 ID - Guha2011 ER - TY - JOUR AU - Banerjee, S. AU - Li, Y. AU - Wang, Z. AU - Sarkar, F. H. PY - 2008 DA - 2008// TI - Multi-targeted therapy of cancer by genistein JO - Cancer Lett VL - 269 ID - Banerjee2008 ER - TY - JOUR AU - Li, Y. AU - Tollefsbol, T. O. PY - 2010 DA - 2010// TI - Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components JO - Curr Med Chem VL - 17 ID - Li2010 ER - TY - JOUR AU - Kikuno, N. AU - Shiina, H. AU - Urakami, S. AU - Kawamoto, K. AU - Hirata, H. AU - Tanaka, Y. PY - 2008 DA - 2008// TI - Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells JO - Int J Cancer VL - 123 ID - Kikuno2008 ER - TY - JOUR AU - Basak, S. AU - Pookot, D. AU - Noonan, E. J. AU - Dahiya, R. PY - 2008 DA - 2008// TI - Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function JO - Mol Cancer Ther VL - 7 ID - Basak2008 ER - TY - JOUR AU - Ye, R. AU - Goodarzi, A. A. AU - Kurz, E. U. AU - Saito, S. AU - Higashimoto, Y. AU - Lavin, M. F. AU - Appella, E. AU - Anderson, C. W. AU - Lees-Miller, S. P. PY - 2004 DA - 2004// TI - The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX JO - DNA Repair VL - 3 ID - Ye2004 ER - TY - JOUR AU - Ding, H. AU - Duan, W. AU - Zhu, W. G. AU - Ju, R. AU - Srinivasan, K. AU - Otterson, G. A. AU - Villalona-Calero, M. A. PY - 2003 DA - 2003// TI - P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells JO - Biochem Biophys Res Commun VL - 305 ID - Ding2003 ER - TY - JOUR AU - Chang, K. L. AU - Kung, M. L. AU - Chow, N. H. AU - Su, S. J. PY - 2004 DA - 2004// TI - Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1 JO - Biochem Pharmacol VL - 67 ID - Chang2004 ER - TY - JOUR AU - Ouyang, G. AU - Yao, L. AU - Ruan, K. AU - Song, G. AU - Mao, Y. AU - Bao, S. PY - 2009 DA - 2009// TI - Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways JO - Cell Biol Int VL - 33 ID - Ouyang2009 ER - TY - JOUR AU - Shiau, R. J. AU - Chen, K. Y. AU - Wen, Y. D. AU - Chuang, C. H. AU - Yeh, S. L. PY - 2010 DA - 2010// TI - Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells JO - Eur J Nutr VL - 49 ID - Shiau2010 ER - TY - JOUR AU - Ide, H. AU - Jingsong, Y. AU - Yan, L. AU - China, T. AU - Kumamoto, T. AU - Koseki, T. AU - Muto, S. AU - Horie, S. PY - 2011 DA - 2011// TI - Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP JO - Cancer Sci VL - 102 ID - Ide2011 ER - TY - JOUR AU - Vauzour, D. AU - Vafeiadou, K. AU - Rice-Evans, C. AU - Cadenas, E. AU - Spencer, J. P. PY - 2007 DA - 2007// TI - Inhibition of cellular proliferation by the genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway JO - Arch Biochem Biophys VL - 468 ID - Vauzour2007 ER - TY - JOUR AU - Regenbrecht, C. R. AU - Jung, M. AU - Lehrach, H. AU - Adjaye, J. PY - 2008 DA - 2008// TI - The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines JO - BMC Med Genomics VL - 1 ID - Regenbrecht2008 ER - TY - JOUR AU - Tominaga, Y. AU - Wang, A. AU - Wang, R. H. AU - Wang, X. AU - Cao, L. AU - Deng, C. X. PY - 2007 DA - 2007// TI - Genistein inhibits Brca1 mutant tumor growth through activation of DNA damage checkpoints, cell cycle arrest, and mitotic catastrophe JO - Cell Death Differ VL - 14 ID - Tominaga2007 ER - TY - JOUR AU - Ismail, I. A. AU - Kang, K. S. AU - Lee, H. A. AU - Kim, J. W. AU - Sohn, Y. K. PY - 2007 DA - 2007// TI - Genistein-induced neuronal apoptosis and G2/M cell cycle arrest is associated with MDC1 up-regulation and PLK1 down-regulation JO - Eur J Pharmacol VL - 575 ID - Ismail2007 ER - TY - JOUR AU - Ullah, M. F. AU - Shamim, U. AU - Hanif, S. AU - Azmi, A. S. AU - Hadi, S. M. PY - 2009 DA - 2009// TI - Cellular DNA breakage by soy isoflavone genistein and its methylated structural analogue biochanin A JO - Mol Nutr Food Res VL - 53 ID - Ullah2009 ER - TY - JOUR AU - Ye, R. AU - Bodero, A. AU - Zhou, B. B. AU - Khanna, K. K. AU - Lavin, M. F. AU - Lees-Miller, S. P. PY - 2001 DA - 2001// TI - The plant isoflavanoid genistein activates p53 and Chk2 in an ATM-dependent manner JO - J Biol Chem VL - 276 ID - Ye2001 ER - TY - JOUR AU - Leung, H. Y. AU - Yung, L. H. AU - Poon, C. H. AU - Shi, G. AU - Lu, A. L. AU - Leung, L. K. PY - 2009 DA - 2009// TI - Genistein protects against polycyclic aromatic hydrocarbon-induced oxidative DNA damage in non-cancerous breast cells MCF-10A JO - Br J Nutr VL - 101 ID - Leung2009 ER - TY - JOUR AU - Lee, W. J. AU - Chen, Y. R. AU - Tseng, T. H. PY - 2011 DA - 2011// TI - Quercetin induces FasL-related apoptosis, in part, through promotion of histone H3 acetylation in human leukemia HL-60 cells JO - Oncol Rep VL - 25 ID - Lee2011 ER - TY - JOUR AU - Yamashita, N. AU - Tanemura, H. AU - Kawanishi, S. PY - 1999 DA - 1999// TI - Mechanism of oxidative DNA damage induced by quercetin in the presence of Cu(II) JO - Mutat Res VL - 425 ID - Yamashita1999 ER - TY - JOUR AU - Tan, J. AU - Wang, B. AU - Zhu, L. PY - 2009 DA - 2009// TI - DNA binding and oxidative DNA damage induced by a quercetin copper(II) complex: potential mechanism of its antitumor properties JO - J Biol Inorg Chem VL - 14 ID - Tan2009 ER - TY - JOUR AU - Izzard, R. A. AU - Jackson, S. P. AU - Smith, G. C. PY - 1999 DA - 1999// TI - Competitive and noncompetitive inhibition of the DNA-dependent protein kinase JO - Cancer Res VL - 59 ID - Izzard1999 ER - TY - JOUR AU - Sebova, K. AU - Fridrichova, I. PY - 2010 DA - 2010// TI - Epigenetic tools in potential anticancer therapy JO - Anticancer Drugs VL - 21 ID - Sebova2010 ER - TY - JOUR AU - Kim, M. S. AU - Blake, M. AU - Baek, J. H. AU - Kohlhagen, G. AU - Pommier, Y. AU - Carrier, F. PY - 2003 DA - 2003// TI - Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA JO - Cancer Res VL - 63 ID - Kim2003 ER - TY - JOUR AU - Ozaki, K. AU - Kishikawa, F. AU - Tanaka, M. AU - Sakamoto, T. AU - Tanimura, S. AU - Kohno, M. PY - 2008 DA - 2008// TI - Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross-resistance to a wide range of DNA damaging drugs JO - Cancer Sci VL - 99 ID - Ozaki2008 ER - TY - JOUR AU - Lee, J. H. AU - Choy, M. L. AU - Ngo, L. AU - Foster, S. S. AU - Marks, P. A. PY - 2010 DA - 2010// TI - Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair JO - Proc Natl Acad Sci USA VL - 107 ID - Lee2010 ER - TY - JOUR AU - Yu, D. AU - Sekine-Suzuki, E. AU - Xue, L. AU - Fujimori, A. AU - Kubota, N. AU - Okayasu, R. PY - 2009 DA - 2009// TI - Chemopreventive agent sulforaphane enhances radiosensitivity in human tumor cells JO - Int J Cancer VL - 125 ID - Yu2009 ER - TY - JOUR AU - Pettazzoni, P. AU - Pizzimenti, S. AU - Toaldo, C. AU - Sotomayor, P. AU - Tagliavacca, L. PY - 2011 DA - 2011// TI - Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells JO - Free Radic Biol Med VL - 50 ID - Pettazzoni2011 ER - TY - JOUR AU - Sahu, R. P. AU - Epperly, M. W. AU - Srivastava, S. K. PY - 2009 DA - 2009// TI - Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy JO - Front Biosci (Elite Ed) VL - 1 ID - Sahu2009 ER - TY - JOUR AU - Hu, Y. AU - Lu, W. AU - Chen, G. AU - Zhang, H. AU - Jia, Y. AU - Wei, Y. AU - Yang, H. AU - Zhang, W. PY - 2010 DA - 2010// TI - Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate JO - Blood VL - 116 ID - Hu2010 ER - TY - CHAP AU - Sukumari-Ramesh, S. AU - Singh, N. AU - Jensen, M. A. AU - Dhandapani, K. M. AU - Vender, J. R. PY - 2011 DA - 2011// TI - Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells BT - J Neurosurg ID - Sukumari-Ramesh2011 ER - TY - JOUR AU - Xiao, H. AU - Zhang, K. J. PY - 2008 DA - 2008// TI - Antiproliferative effect of curcumin combined with cyclophosmide on the growth of human lymphoma cell line HT/CTX with drug resistance and its relation with FA/BRCA pathway JO - Zhongguo Shi Yan Xue Ye Xue Za Zhi VL - 16 ID - Xiao2008 ER - TY - JOUR AU - Xiao, H. AU - Xiao, Q. AU - Zhang, K. AU - Zuo, X. AU - Shrestha, U. K. PY - 2010 DA - 2010// TI - Reversal of multidrug resistance by curcumin through FA/BRCA pathway in multiple myeloma cell line MOLP-2/R JO - Ann Hematol VL - 89 ID - Xiao2010 ER - TY - JOUR AU - Du, B. AU - Jiang, L. AU - Xia, Q. AU - Zhong, L. PY - 2006 DA - 2006// TI - Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29 JO - Chemotherapy VL - 52 ID - Du2006 ER - TY - JOUR AU - Lev-Ari, S. AU - Strier, L. AU - Kazanov, D. AU - Madar-Shapiro, L. AU - Dvory-Sobol, H. PY - 2005 DA - 2005// TI - Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells JO - Clin Cancer Res VL - 11 ID - Lev-Ari2005 ER - TY - JOUR AU - Ji, Z. PY - 2010 DA - 2010// TI - Targeting DNA damage and repair by curcumin JO - Breast Cancer VL - 4 ID - Ji2010 ER - TY - JOUR AU - Tsai, M. S. AU - Weng, S. H. AU - Kuo, Y. H. AU - Chiu, Y. F. AU - Lin, Y. W. PY - 2011 DA - 2011// TI - Synergistic effect of curcumin and cisplatin via downregulation of thymidine phosphorylase and ERCC1 JO - Mol Pharmacol VL - 80 ID - Tsai2011 ER - TY - JOUR AU - Giommarelli, C. AU - Zuco, V. AU - Favini, E. AU - Pisano, C. AU - Dal Piaz, F. AU - De Tommasi, N. AU - Zunino, F. PY - 2010 DA - 2010// TI - The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition JO - Cell Mol Life Sci VL - 67 ID - Giommarelli2010 ER - TY - JOUR AU - Podhorecka, M. AU - Halicka, D. AU - Klimek, P. AU - Kowal, M. AU - Chocholska, S. AU - Dmoszynska, A. PY - 2011 DA - 2011// TI - Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia JO - Ann Hematol VL - 90 ID - Podhorecka2011 ER - TY - JOUR AU - Wolff, G. L. AU - Kodell, R. L. AU - Moore, S. R. AU - Cooney, C. A. PY - 1998 DA - 1998// TI - Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice JO - FASEB J VL - 12 ID - Wolff1998 ER - TY - JOUR AU - Poirier, L. A. PY - 1994 DA - 1994// TI - Methyl group deficiency in hepatocarcinogenesis JO - Drug Metab Rev VL - 26 ID - Poirier1994 ER - TY - JOUR AU - Davis, C. D. AU - Uthus, E. O. AU - Finley, J. W. PY - 2000 DA - 2000// TI - Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells and in vivo in rat liver and colon JO - J Nutr VL - 130 ID - Davis2000 ER - TY - JOUR AU - Weaver, I. C. AU - Cervoni, N. AU - Champagne, F. A. AU - D'Alessio, A. C. AU - Sharma, S. AU - Seckl, J. R. PY - 2004 DA - 2004// TI - Epigenetic programming by maternal behavior JO - Nat Neurosci VL - 7 ID - Weaver2004 ER - TY - JOUR AU - Weaver, I. C. AU - Meaney, M. J. AU - Szyf, M. PY - 2006 DA - 2006// TI - Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood JO - Proc Natl Acad Sci USA VL - 103 ID - Weaver2006 ER - TY - JOUR AU - Murugan, R. S. AU - Vinothini, G. AU - Hara, Y. AU - Nagini, S. PY - 2009 DA - 2009// TI - Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model JO - Anticancer Res VL - 29 ID - Murugan2009 ER - TY - JOUR AU - Cosio, B. G. AU - Mann, B. AU - Ito, K. AU - Jazrawi, E. AU - Barnes, P. J. AU - Chung, K. F. PY - 2004 DA - 2004// TI - Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma JO - Am J Respir Crit Care Med VL - 170 ID - Cosio2004 ER - TY - JOUR AU - Cosio, B. G. AU - Tsaprouni, L. AU - Ito, K. AU - Jazrawi, E. AU - Adcock, I. M. AU - Barnes, P. J. PY - 2004 DA - 2004// TI - Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages JO - J Exp Med VL - 200 ID - Cosio2004 ER - TY - JOUR AU - Cosio, B. G. AU - Iglesias, A. AU - Rios, A. AU - Noguera, A. AU - Sala, E. AU - Ito, K. PY - 2009 DA - 2009// TI - Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD JO - Thorax VL - 64 ID - Cosio2009 ER - TY - JOUR AU - Ito, K. AU - Lim, S. AU - Caramori, G. AU - Cosio, B. AU - Chung, K. F. AU - Adcock, I. M. PY - 2002 DA - 2002// TI - A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression JO - Proc Natl Acad Sci USA VL - 99 ID - Ito2002 ER - TY - JOUR AU - Priyadarsini, R. V. AU - Vinothini, G. AU - Murugan, R. S. AU - Manikandan, P. AU - Nagini, S. PY - 2011 DA - 2011// TI - The flavonoid Quercetin modulates the hallmark capabilities of hamster buccal pouch tumors JO - Nutr Cancer VL - 63 ID - Priyadarsini2011 ER - TY - JOUR AU - Hu, R. AU - Khor, T. O. AU - Shen, G. AU - Jeong, W. S. AU - Hebbar, V. AU - Chen, C. PY - 2006 DA - 2006// TI - Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable JO - Carcinogenesis VL - 27 ID - Hu2006 ER - TY - JOUR AU - Myzak, M. C. AU - Dashwood, W. M. AU - Orner, G. A. AU - Ho, E. AU - Dashwood, R. H. PY - 2006 DA - 2006// TI - Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice JO - FASEB J VL - 20 ID - Myzak2006 ER - TY - JOUR AU - Myzak, M. C. AU - Tong, P. AU - Dashwood, W. M. AU - Dashwood, R. H. AU - Ho, E. PY - 2007 DA - 2007// TI - Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects JO - Exp Biol Med VL - 232 ID - Myzak2007 ER - TY - CHAP AU - Clarke, J. D. AU - Hsu, A. AU - Williams, D. E. AU - Dashwood, R. H. AU - Stevens, J. F. AU - Yamamoto, M. AU - Ho, E. PY - 2011 DA - 2011// TI - Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice BT - Pharm Res ID - Clarke2011 ER - TY - JOUR AU - Ji, Y. AU - Kuo, Y. AU - Morris, M. E. PY - 2005 DA - 2005// TI - Pharmacokinetics of dietary phenethylisothiocyanate in rats JO - Pharm Res VL - 22 ID - Ji2005 ER - TY - JOUR AU - Ye, L. AU - Dinkova-Kostova, A. T. AU - Wade, K. L. AU - Zhang, Y. AU - Shapiro, T. A. AU - Talalay, P. PY - 2002 DA - 2002// TI - Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans JO - Clin Chim Acta VL - 316 ID - Ye2002 ER - TY - JOUR AU - Druesne-Pecollo, N. AU - Chaumontet, C. AU - Pagniez, A. AU - Vaugelade, P. AU - Bruneau, A. AU - Thomas, M. PY - 2007 DA - 2007// TI - In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes JO - Biochem Biophys Res Commun VL - 354 ID - Druesne-Pecollo2007 ER - TY - JOUR AU - Zhao, J. AU - Huang, W. G. AU - He, J. AU - Tan, H. AU - Liao, Q. J. AU - Su, Q. PY - 2006 DA - 2006// TI - Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAF1 expression in vivo and in vitro JO - Acta Pharmacol Sin VL - 27 ID - Zhao2006 ER - TY - CHAP AU - Tyagi, A. AU - Gu, M. AU - Takahata, T. AU - Frederick, B. A. AU - Agarwal, C. AU - Siriwardana, S. AU - Agarwal, R. AU - Sclafani, R. A. PY - 2011 DA - 2011// TI - Resveratrol selectively induces DNA damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma BT - Clin Cancer Res ID - Tyagi2011 ER - TY - JOUR AU - Vanhees, K. AU - de Bock, L. AU - Godschalk, R. W. AU - van Schooten, F. J. AU - van Waalwijk van Doorn-Khosrovani, S. B. PY - 2011 DA - 2011// TI - Prenatal exposure to flavonoids: implication for cancer risk JO - Toxicol Sci VL - 120 ID - Vanhees2011 ER - TY - JOUR AU - Toyoizumi, T. AU - Sekiguchi, H. AU - Takabayashi, F. AU - Deguchi, Y. AU - Masuda, S. AU - Kinae, N. PY - 2010 DA - 2010// TI - Induction effect of coadministration of soybean isoflavones and sodium nitrite on DNA damage in mouse stomach JO - Food Chem Toxicol VL - 48 ID - Toyoizumi2010 ER - TY - JOUR AU - Amin, A. R. AU - Wang, D. AU - Zhang, H. AU - Peng, S. AU - Shin, H. J. AU - Brandes, J. C. AU - Tighiouart, M. AU - Khuri, F. R. AU - Chen, Z. G. AU - Shin, D. M. PY - 2010 DA - 2010// TI - Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53 JO - J Biol Chem VL - 285 ID - Amin2010 ER - TY - JOUR AU - Mueller, S. AU - Yang, X. AU - Sottero, T. L. AU - Gragg, A. AU - Prasad, G. AU - Polley, M. Y. AU - Weiss, W. A. AU - Matthay, K. K. AU - Davidoff, A. M. AU - DuBois, S. G. AU - Haas-Kogan, D. A. PY - 2011 DA - 2011// TI - Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms JO - Cancer Lett VL - 306 ID - Mueller2011 ER - TY - JOUR AU - Di Micco, R. AU - Sulli, G. AU - Dobreva, M. AU - Liontos, M. AU - Botrugno, O. A. AU - Gargiulo, G. AU - dal Zuffo, R. AU - Matti, V. PY - 2011 DA - 2011// TI - Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer JO - Nat Cell Biol VL - 13 ID - Di Micco2011 ER - TY - JOUR AU - Baschnagel, A. AU - Russo, A. AU - Burgan, W. E. AU - Carter, D. AU - Beam, K. AU - Palmieri, D. AU - Steeg, P. S. AU - Tofilon, P. AU - Camphausen, K. PY - 2009 DA - 2009// TI - Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts JO - Mol Cancer Ther VL - 8 ID - Baschnagel2009 ER - TY - JOUR AU - Camphausen, K. AU - Scott, T. AU - Sproull, M. AU - Tofilon, P. J. PY - 2004 DA - 2004// TI - Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation JO - Clin Cancer Res VL - 10 ID - Camphausen2004 ER - TY - JOUR AU - Camphausen, K. AU - Cerna, D. AU - Scott, T. AU - Sproull, M. AU - Burgan, W. E. AU - Cerra, M. A. AU - Fine, H. AU - Tofilon, P. J. PY - 2005 DA - 2005// TI - Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid JO - Int J Cancer VL - 114 ID - Camphausen2005 ER - TY - JOUR AU - Geng, L. AU - Cuneo, K. C. AU - Fu, A. AU - Tu, T. AU - Atadja, P. W. AU - Hallahan, D. E. PY - 2006 DA - 2006// TI - Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated nonsmall cell lung cancer JO - Cancer Res VL - 66 ID - Geng2006 ER - TY - JOUR AU - Cuneo, K. C. AU - Fu, A. AU - Osusky, K. AU - Huamani, J. AU - Hallahan, D. E. AU - Geng, L. PY - 2007 DA - 2007// TI - Histone deacetylase inhibitor NVP-LAQ824 sensitizes human nonsmall cell lung cancer to the cytotoxic effects of ionizing radiation JO - Anticancer Drugs VL - 18 ID - Cuneo2007 ER - TY - JOUR AU - Entin-Meer, M. AU - Yang, X. AU - VandenBerg, S. R. AU - Lamborn, K. R. AU - Nudelman, A. AU - Rephaeli, A. AU - Haas-Kogan, D. A. PY - 2007 DA - 2007// TI - In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas JO - Neuro Oncol VL - 9 ID - Entin-Meer2007 ER - TY - JOUR AU - Lopez, G. AU - Liu, J. AU - Ren, W. AU - Wei, W. AU - Wang, S. AU - Lahat, G. AU - Zhu, Q. S. AU - Bornmann, W. G. AU - McConkey, D. J. AU - Pollock, R. E. AU - Lev, D. C. PY - 2009 DA - 2009// TI - Combining PCI-24781, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma JO - Clin Cancer Res VL - 15 ID - Lopez2009 ER - TY - JOUR AU - Purrucker, J. C. AU - Fricke, A. AU - Ong, M. F. AU - Rübe, C. AU - Rübe, C. E. AU - Mahlknecht, U. PY - 2010 DA - 2010// TI - HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA Double-Strand Break repair capacity JO - Oncol Rep VL - 23 ID - Purrucker2010 ER - TY - JOUR AU - Wang, L. H. AU - Pfister, T. D. AU - Parchment, R. E. AU - Kummar, S. AU - Rubinstein, L. AU - Evrard, Y. A. AU - Gutierrez, M. E. AU - Murgo, A. J. AU - Tomaszewski, J. E. AU - Doroshow, J. H. AU - Kinders, R. J. PY - 2010 DA - 2010// TI - Monitoring drug induced gammaH2AX as a pharmacodynamic biomarker in individual circulating tumor cells JO - Clin Cancer Res VL - 16 ID - Wang2010 ER - TY - JOUR AU - Fong, P. C. AU - Boss, D. S. AU - Yap, T. A. AU - Tutt, A. AU - Wu, P. AU - Mergui-Roelvink, M. AU - Mortimer, P. PY - 2009 DA - 2009// TI - Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers JO - N Engl J Med VL - 361 ID - Fong2009 ER - TY - JOUR AU - Redon, C. E. AU - Nakamura, A. J. AU - Zhang, Y. W. AU - Ji, J. J. AU - Bonner, W. M. AU - Kinders, R. J. AU - Parchment, R. E. AU - Doroshow, J. H. AU - Pommier, Y. PY - 2010 DA - 2010// TI - Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers JO - Clin Cancer Res VL - 16 ID - Redon2010 ER - TY - JOUR AU - Zupkovitz, G. AU - Grausenburger, R. AU - Brunmeir, R. AU - Senese, S. AU - Tischler, J. PY - 2010 DA - 2010// TI - The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation JO - Mol Cell Biol VL - 30 ID - Zupkovitz2010 ER -