Skip to main content

Table 4 Linear regression analysis: DNA methylation at IGF2 and H19 DMRs in the offspring in relation to maternal depression and the use of antidepressants, in African American and in Caucasian participants

From: The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring

 

IGF2 DMR

H19 DMR

 

Caucasian

n 1 = 159

African American n 1 = 172

Caucasian

n 1 = 168

African American n 1 = 177

 

β

SE

p

β

SE

p

β

SE

p

Î’

SE

p

Model 12:

Antidepressant use

-1.41

1.27

0.27

+1.63

2.58

0.53

-2.04

1.67

0.22

+6.89

2.53

0.01

Model 22:

Depression

+1.10

1.26

0.38

+0.29

1.69

0.86

+0.15

1.70

0.93

+0.07

1.89

0.97

  1. 1 Number of observations in the statistical analysis.
  2. 2 At IGF2 DMR: adjusted for age, education, and smoking during pregnancy.
  3. 2 At H19 DMR: adjusted for age, smoking during pregnancy, marital status, education, BMI, and birth weight.