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Table 3 Multiple linear regression analyses: DNA methylation at IGF2 and H19 DMR in the offspring in relation to the use of antidepressants, depression, and race of the mother

From: The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring

  IGF2 DMR
n max.1 = 356
H19 DMR
n max. 1 = 411
  β SE p β SE p
Model 12:
Antidepressant use
-0.47 1.28 0.71 +0.54 1.40 0.70
Model 22:
Depression
+0.72 1.06 0.50 +0.25 1.25 0.84
Model 3 2 , interaction with race:
Antidepressant use
Race (being African American)
Antidepressants × Race (African American)
-1.63
+0.40
+3.58
1.55
0.92
2.71
0.29
0.66
0.19
-2.38
-0.01
+9.18
1.67
1.17
2.95
0.16
0.99
0.002
  1. 1 Number included in the statistical analyses, this may vary slightly by missing variables in the different models.
  2. 2 At IGF2 DMR: adjusted for age, race, education, and smoking during pregnancy.
  3. 2 At H19 DMR: adjusted for age, race, smoking during pregnancy, marital status, education, BMI, and birth weight.