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Table 2 DNA methylation at IGF2 DMR and H19 DMR sites by socio-demographic characteristics

From: The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring

   IGF2 DMR mean methylation% n = 356 (SD) Δ (p-value) H19 DMR mean methylation% n = 411 (SD) Δ (p-value)
Total:   47.45 (6.89)   60.09 (7.89)  
Maternal age: < 30 47.43 (7.29) +0.05 (0.95) 60.01 (7.44) +0.18 (0.81)
  ≥30 47.48 (6.40)   60.19 (8.42)  
Marital status: living with partner 47.10 (6.59) +0.97 (0.20) 59.48 (7.59) +1.63 (0.05)
  single 48.07 (7.37)   61.11 (8.30)  
Race1: African American 47.62 (7.96) -0.52 (0.49) 61.00 (7.90) -1.80 (0.03)
  Caucasian 47.10 (5.60)   59.20 (7.60)  
College graduate: no 47.72 (7.04) -0.73 (0.34) 60.73 (8.07) -1.83 (0.03)
  yes 46.99 (6.61)   58.90 (7.45)  
Antidepressant use: no 47.44 (7.06) +0.17 (0.85) 60.12 (7.63) -0.25 (0.87)
  yes 47.61 (5.07)   59.87 (9.98)  
Depression: no 47.21 (6.65) +1.52 (0.13) 60.18 (8.00) -0.07 (0.95)
  yes 48.74 (8.00)   60.11 (7.64)  
BMI: ≤ 30 47.81 (7.10) -0.71 (0.41) 59.51 (7.33) +1.81 (0.07)
  > 30 47.10 (7.01)   61.32 (9.02)  
Smoking 1 year non-smoker 47.69 (7.15) -0.94 (0.24) 60.24 (7.90) -0.53 (0.54)
before pregnancy: smoker 46.75 (6.25)   59.71 (7.00)  
Smoking during non-smoker 46.82 (5.84) +3.05 (0.01) 60.07 (7.83) +0.14 (0.88)
pregnancy: smoker 49.87 (9.62)   60.22 (8.22)  
Birth weight: < 2500 g 47.57 (8.24) -0.14 (0.91) 58.96 (5.32) +1.34 (0.15)
  ≥2500 g 47.43 (6.67)   60.30 (7.58)  
Gender of newborn: male 47.05 (5.86) +0.80 (0.28) 59.67 (7.93) +0.85 (0.28)
  female 47.85 (6.63)   60.52 (7.95)  
  1. 1 Only the data from children born to Caucasian and African American women are included; numbers of other races were too low.