Skip to main content

Table 1 Distribution of depression and intake of antidepressants in 436 study participants by socio-demographic characteristics in the Newborn Epigenetics Study (NEST), NC, 2005-2008

From: The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring

Socio-demographic data

 

Depression

Antidepressant use

Subgroup

n 1

% 1

n

%

p-value

n

%

p-value

Total:

 

436

100

66

15.1

 

44

10.1

 

Maternal age:

< 30

240

55.1

44

18.3

0.04

20

8.3

0.18

 

≥30

196

44.9

22

11.2

 

24

12.2

 

Marital status:

living with partner

276

63.3

38

13.8

0.30

30

10.9

0.48

 

single

160

36.7

28

17.5

 

14

8.8

 

Race2:

African American

215

49.3

33

15.4

0.95

14

6.5

0.01

 

Caucasian

193

44.3

30

15.5

 

28

14.5

 

College graduate:

no

284

65.1

55

19.4

0.0004

31

10.9

0.45

 

yes

151

34.6

10

6.6

 

13

8.6

 

Antidepressant use:

no

392

89.9

46

11.7

< 0.0001

 
 

yes

44

10.1

20

45.5

  

Depression:

no

370

84.9

 

24

6.5

< 0.0001

 

yes

66

15.1

 

20

30.3

 

BMI:

< 18

13

3.0

4

30.8

0.14

2

15.4

0.54

 

18- < 25

189

43.4

24

12.7

 

13

6.9

 
 

25-30

82

18.8

13

15.8

 

10

12.2

 
 

> 30

111

25.5

14

12.6

 

14

12.6

 

Smoking 1 year before

non-smoker

305

70.0

46

15.1

0.92

30

9.8

0.82

pregnancy:

smoker

123

28.2

19

15.4

 

13

10.6

 

Smoking during

non-smoker

347

79.6

37

10.7

< 0.0001

29

8.4

0.02

pregnancy:

smoker

88

20.2

29

33.0

 

15

17.1

 

Birth weight:

< 2500 g

59

13.5

10

16.9

0.80

10

15.2

0.11

 

≥2500 g

369

84.6

54

14.6

 

34

9.2

 

Gender of newborn:

male

221

50.7

35

15.8

0.60

19

8.6

0.24

 

female

207

47.5

29

14.0

 

25

12.1

 
  1. 1 The sum of the numbers (or percentages) for each characteristic are not always 436 (or 100), because some data were missing.
  2. 2 Other races were: Asian (n = 7), Native American (n = 2), or not listed (n = 13).