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Table 2 Comparative analysis of genomic 5-mdC levels between Dnmt1+/+ and Dnmt1+/− mice

From: Insufficient DNA methylation affects healthy aging and promotes age-related health problems

Age (month)

Percentage of genomic 5-mdC

Dnmt1+/+

Dnmt1+/−

Brain cortex

3

4.62

4.52

11

4.32

4.07

17

4.24

4.1

Brain hippocampus

3

4.08

3.98

11

3.97

3.84

17

3.85

3.87

  1. The % value of 5-mdC is expressed as a ratio of 5-mdC to all deoxyguanosine (dG). Each value represents the mean of the results from two different mice, and no statistical analysis was applied