From: Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation
Gene ID | ChIP-Seq detected | gPCR confirmed | RT-PCR (fold change) | Pubmed ID | Chromo | Gene description | Antag vs. control (fold change) | HP1β siRNA vs control (fold change) |
---|---|---|---|---|---|---|---|---|
FAM13A | Yes | Yes | 2.4 ± 0.6 | 10,144 | 4 | Family with sequence similarity 13, member A | 2.4 | 5.5 |
GBE1 | Yes | Yes | 3.3 ± 0.7 | 2,632 | 3 | Glucan (1,4-alpha-), branching enzyme 1 | 2.8 | 4.2 |
PLK3 | Yes | Yes | 2.8 ± 0.7 | 1,263 | 1 | Polo-like kinase 3 | 2.0 | 2.6 |
SLCO1B3 | Yes | Yes | 4.2 ± 2.12 | 28,234 | 12 | Solute carrier organic anion transporter family, member 1B3 | 2.0 | 3.5 |
PLOD2 | Yes | No | n.r. | 5,352 | 3 | Procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 | 2.2 | 5.2 |
ACSF2 | No | No | n.r. | 80,221 | 17 | Acyl-CoA synthetase family member 2 | 2.1 | 2.3 |
AKAP7 | No | No | n.r. | 9,465 | 6 | A kinase (PRKA) anchor protein 7 | 5.0 | 14.1 |
APOL1 | No | No | n.r. | 8,542 | 22 | apolipoprotein L, 1 | 2.0 | 3.0 |
ARL14 | No | No | n.r. | 80,117 | 3 | ADP-ribosylation factor-like 14 | 2.4 | 4.6 |
BCL3 | No | No | n.r. | 602 | 19 | B-cell CLL/lymphom a 3 | 3.4 | 3.5 |
BDH2 | No | No | n.r. | 56,898 | 4 | 3-hydroxybutyrate dehydrogenase, type 2 | 2.0 | 3.1 |
BNIP3L | No | No | n.r. | 665 | 8 | BCL2/adenovirus E1B 19 kDa interacting protein 3-like | 2.4 | 6.0 |
CCDC64 | No | No | n.r. | 92,558 | 12 | Coiled-coil domain containing 64 | 2.1 | 3.0 |
CDKN1A | No | No | n.r. | 12,575 | 17 | Cyclin dependent kinase inhibitor 1A (P21) | 2.5 | 4.8 |
CDKN1C | No | No | n.r. | 1,028 | 11 | Cyclin dependent kinase inhibitor 1 C (p57, Kip2) | 3.3 | 7.6 |
CLIC3 | No | No | n.r. | 9022 | 9 | Chloride intracellular channel 3 | 2.7 | 3.0 |
CYP3A5P2 | No | No | n.r. | 79,424 | 7 | Cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 | 2.2 | 2.4 |
DUSP6 | No | No | n.r. | 1,848 | 12 | Dual specificity phosphatase 6 | 2.1 | 2.5 |
ENO2 | No | No | n.r. | 2,026 | 12 | Enolase 2 (gamma, neuronal) | 3.0 | 4.9 |
FABP1 | No | No | n.r. | 2,168 | 2 | Fatty acid binding protein 1, liver | 3.2 | 2.8 |
FOSL1 | No | No | n.r. | 8,061 | 11 | FOS-like antigen 1 | 3.0 | 2.2 |
FSCN1 | No | No | n.r. | 6,624 | 7 | Fascin homolog 1, actin-bundling protein (Strongylocent rotus purpuratus) | 3.1 | 3.8 |
FXYD3 | No | No | n.r. | 5,349 | 19 | FXYD domain containing ion transport regulator 3 | 2.4 | 4.1 |
GAL3ST1 | No | No | n.r. | 9,514 | 22 | Galactose-3-Osulfotransferase 1 | 2.0 | 2.9 |
GEM | No | No | n.r. | 2,669 | 8 | GTP binding protein overexpressed in skeletal muscle | 3.8 | 5.2 |
GPR87 | No | No | n.r. | 53,836 | 3 | G protein coupled receptor 87 | 5.3 | 2.5 |
HMGCS2 | No | No | n.r. | 3,158 | 1 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 2.6 | 2.6 |
HRH1 | No | No | n.r. | 3,269 | 3 | Histamine receptor H1 | 2.3 | 2.9 |
KDM4B | No | No | n.r. | 23,030 | 19 | Lysine (K)-specific demethylase 4B | 2.4 | 2.9 |
LAMA3 | No | No | n.r. | 3,909 | 18 | Laminin, alpha 3 | 2.4 | 2.1 |
LDLR | No | No | n.r. | 3,949 | 19 | Low density lipoprotein receptor | 2.1 | 2.7 |
LGALS1 | No | No | n.r. | 3,956 | 22 | Lectin, galactosidebinding, soluble, 1 | 2.2 | 2.5 |
MAFF | No | No | n.r. | 23,764 | 22 | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F | 2.0 | 3.8 |
NAB2 | No | No | n.r. | 4,665 | 12 | NGFI-A binding protein 2 (EGR1 binding protein 2) | 2.1 | 3.2 |
NDRG1 | No | No | n.r. | 10,397 | 8 | N-myc downstream regulated 1 | 5.7 | 18.5 |
NDUFA4L2 | No | No | n.r. | 56,901 | 12 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 9.8 | 9.2 |
P4HA1 | No | No | n.r. | 5,033 | 10 | Prolyl 4-hydroxylase, alpha polypeptide I | 3.2 | 7.9 |
PDE9A | No | No | n.r. | 5,152 | 21 | Phosphodiesterase 9A | 2.0 | 2.5 |
PER2 | No | No | n.r. | 8,864 | 2 | Period homolog 2 (Drosophila) | 2.5 | 3.5 |
PHLDA1 | No | No | n.r. | 22,822 | 12 | Pleckstrin homology-like domain, family A, member 1 | 2.2 | 3.9 |
PTK6 | No | No | n.r. | 5,753 | 20 | PTK6 protein tyrosine kinase 6 | 2.2 | 2.4 |
PTPRH | No | No | n.r. | 5,794 | 19 | Protein tyrosine phosphatase, receptor type, H | 2.1 | 2.3 |
PTPRR | No | No | n.r. | 5,801 | 12 | Protein tyrosine phosphatase, receptor type, R | 6.5 | 12.0 |
RARRES1 | No | No | n.r. | 5918 | 3 | Retinoic acid receptor responder (tazarotene induced) 1 | 2.4 | 3.8 |
RHOF | No | No | n.r. | 54,509 | 12 | Ras homolog gene family, member F (in filopodia) | 2.1 | 3.1 |
SCARF1 | No | No | n.r. | 8,578 | 17 | Scavenger receptor class F, member 1 | 2.5 | 4.2 |
SGK1 | No | No | n.r. | 6,446 | 6 | Serum/glucoco rticoid regulated kinase 1 | 2.1 | 3.2 |
SERPINB9 | No | No | n.r. | 5,272 | 6 | Serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 2.5 | 3.8 |
SLC11A2 | No | No | n.r. | 4,891 | 12 | Solute carrier family 11 8(proton-coupled divalent metal ion) | 3.0 | 3.7 |
SPAG4 | No | No | n.r. | 6,676 | 20 | Sperm associated antigen 4 | 3.5 | 4.8 |
TFF2 | No | No | n.r. | 7,032 | 21 | Trefoil factor 2 | 2.3 | 2.5 |
ZNF274 | No | No | n.r. | 10,782 | 19 | Zinc finger protein 274 | 3.1 | 3.2 |