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Table 1 Genes identified by microarray, ChIP-Seq, and genomic PCR as down-regulated subsequent

From: Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation

Gene ID

ChIPSeq detected

gPCR confirmed

RT-PCR (fold change)

Pubmed ID

Chromo

Gene description

Antag vs. control (fold change)

HP1β siRNA vs. control (fold change)

IL1RAPL2

Yes

Yes

5.6 ± 1.8

26,280

X

Interleukin 1 receptor accessory protein-like 2

4.8

5.4

HSF2BP

Yes

No

n.r.

11,077

21

Heat shock transcription factor 2 binding protein

2.3

3.2

BOP1

No

No

n.r.

23,246

3

Block of proliferation 1

3.2

4.0

CYP27B1

No

No

n.r.

1,594

12

Cytochrome P450, family 27, subfamily B, polypeptide 1

4.0

5.4

KIR2DL5A

No

No

n.r.

57,292

19

Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic

4.8

6.4

TNFRSF11B

No

No

n.r.

4,982

8

TNFRSF11B tumor necrosis factor receptor superfamily, member 11b

3.4

2.6

TNP2

No

No

n.r.

7,142

16

Transition protein 2

3.1

4.0

UTP20

No

No

n.r.

27,340

12

TP20, small subunit (SSU) processome component, homolog

3.2

3.7

WWP2

No

No

n.r.

11,060

16

WW domain containing E3 ubiquitin protein ligase 2

3.6

4.6

  1. Antag: GRPR Specific Antagonist RC-3095. Chromo: Chromosome on which gene is located