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Table 1 Comparison of % activity (average of three sets of independent experiments) of the enzymes without and with increasing concentration of drug

From: 5-Aza-2′-deoxycytidine stress response and apoptosis in prostate cancer

Enzymes Control 5-AzadC (nM)
10 20 35 50 75 100 250 500
DNMT 100 71.23 50.36 5.14 2.32
HDAC 100 90.62 81.07 nd 73.34 61.58 nd nd nd
Caspase-3 2.3 ± 1.73 5.67 ± 3.46 27.5 ± 8.40 41.49 ± 7.0
  1. nd not detected