Fig. 2
From: Epigenetic targets of bioactive dietary components for cancer prevention and therapy
Schematic representation of histone modifications. HATs induce relaxed chromatin which allows access to the various transcriptional factors associated with gene activation. HDACs induce closed chromatin associated with gene activation. Various bioactive compounds such as EGCG, sulforaphane, and curcumin are linked with alterations of both HATs and HDACs. Yellow circle histone protein, red thread DNA; AC acetylation, TF transcription factor