Fig. 1

Epigenetic treatment: the super-selective therapy approach or wide collateral damages. While there is a steadily growing knowledge of the epigenetic influence on malignant cells, little is still known about drug-induced epigenetic modifications on healthy human cells. a Selective influence on tumour cells (blue). b Surrounding tissue maybe affected as well (green). c Wide effects on both tumour and healthy tissue (red). (Schematic; modified CT scans based on Osirix® DICOM image samples)